Human Adiponectin / Acrp30 / ADIPOQ Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant Adiponectin / Acrp30 / ADIPOQ based upon sequence from: Human
Host: QP5279 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Bioactive
Application Notes: Please contact us for application specific information for QP5279.
Bioactivity Data: gACRP (globular adiponectin) activity was confirmed by measuring inhibition of cytotoxicity of M1 cells. Typical ED50 values for our recombinant adiponectin in this assay are in the range of 3 ug/ml.
Monomer or Dimer: Monomer
Amino Acid Sequence: MKGEPGEGAY VYRSAFSVGL ETYVTIPNMP IRFTKIFYNQ QNHYDGSTGK FHCNIPGLYY FAYHITVYMK DVKVSLFKKD KAMLFTYDQY QENNVDQASG SVLLHLEVGD QVWLQVYGEG ERNGLYADND NDSTFTGFLL YHDTN
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Adiponectin / Acrp30 / ADIPOQ Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 5.00 EUs/ug as determined by the LAL method.
Buffer: 10 mM Tris, 0.75 mM DTT, pH 8.0
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.
Recombinant Human Adiponectin / Acrp30 / ADIPOQ Protein General Information | |
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Alternate Names | |
Adiponectin, Acrp30, ADIPOQ, GBP28, adipo, Acdc, APN, Ad, 30kDa, Acrp30, apM1 | |
Curated Database and Bioinformatic Data | |
Gene Symbol | ADIPOQ |
Entrez Gene ID | 9370 |
Ensemble Gene ID | ENSG00000181092 |
RefSeq Protein Accession(s) | NP_001171271.1 |
RefSeq mRNA Accession(s) | NM_001177800.1, NM_004797.3 |
UniProt ID(s) | Q15848 |
UniGene ID(s) | Hs.80485 |
HGNC ID(s) | HGNC:13633 |
COSMIC ID Link(s) | ADIPOQ |
KEGG Gene ID(s) | hsa:9370 |
PharmGKB ID(s) | PA134933118 |
General Description of Recombinant Human Adiponectin / Acrp30 / ADIPOQ Protein . | |
The globular subunit of adipocyte complement-related protein of 30 kDa (gACRP30) is a naturally occurring cleavage product of adiponectin, a protein made exclusively by adipocytes. gACRP30 is an abundant serum protein and plays an important role in hyperglycemia, insulin resistance, and fatty acid oxidation. gACRP30 signals through adiponectin receptor 1 (AdipoR1) and adiponectin receptor 2 (AdipoR2). |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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