PDF DatasheetBovine Adiponectin / Acrp30 / ADIPOQ Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Adiponectin / Acrp30 / ADIPOQ based upon sequence from: Bovine
Host: QP7647 protein expressed in E.coli, Yeast..
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Bos taurus (Bovine) Adiponectin / Acrp30 / ADIPOQ, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP7647.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Glu18 – Glu240
Amino Acid Sequence: EDNMEDPPLP KGACAGWMAG IPGHPGHNGT PGRDGRDGTP GEKGEKGDPG LVGPKGDTGE TGITGIEGPR GFPGTPGRKG EPGESAYVYR SAFSVGLERQ VTVPNVPIRF TKIFYNQQNH YDGTTGKFLC NIPGLYYFSY HITVYLKDVK VSLYKNDKAL LFTHDQFQDK NVDQASGSVL LYLEKGDQVW LQVYEGENHN GVYADNVNDS TFTGFLLYHN IVE
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Bovine Adiponectin / Acrp30 / ADIPOQ Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Bovine Adiponectin / Acrp30 / ADIPOQ Protein General Information | |
|---|---|
| Alternate Names | |
| Adiponectin; Acrp30; ADIPOQ; GBP28; adipo; Acdc; APN; Ad; 30kDa; Acrp30; apM1 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | ADIPOQ |
| Entrez Gene ID | 282865 |
| Ensemble Gene ID | ENSBTAG00000019813 |
| RefSeq Protein Accession(s) | NP_777167.1 |
| RefSeq mRNA Accession(s) | NM_174742.2 |
| UniProt ID(s) | Q3Y5Z3 |
| UniGene ID(s) | Bt.109637 |
| COSMIC ID Link(s) | ADIPOQ |
| KEGG Gene ID(s) | bta:282865 |
| General Description of Recombinant Bovine Adiponectin / Acrp30 / ADIPOQ Protein. | |
| Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue rodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW . | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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