PDF DatasheetHuman BLyS / TNFSF13B / BAFF Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant BLyS / TNFSF13B / BAFF based upon sequence from: Human
Host: QP5331 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Immunogen, Protein Standard, Other Cell Biology Applications
Application Notes: Please contact us for application specific information for QP5331.
Bioactivity Data: Untested
Monomer or Dimer: Monomer
Amino Acid Sequence: MHHHHHHLVP RAVQGPEETV TQDCLQLIAD SETPTIQKGS YTFVPWLLSF KRGSALEEKE NKILVKETGY FFIYGQVLYT DKTYAMGHLI QRKKVHVFGD ELSLVTLFRC IQNMPETLPN NSCYSAGIAK LEEGDELQLA IPRENAQISL DGDVTFFGAL KLL
Purity: Greater than 90 as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human BLyS / TNFSF13B / BAFF Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: 10 mM sodium phosphate, pH 7.5
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.
| Recombinant Human BLyS / TNFSF13B / BAFF Protein General Information | |
|---|---|
| Alternate Names | |
| BLyS, TNFSF13B, BAFF, TNFSF20, DTL, THANK, ZTNF4, BLYS, CD257, TALL1, TNLG7A, BAFF, TALL-1 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | TNFSF13B |
| Entrez Gene ID | 10673 |
| Ensemble Gene ID | ENSG00000102524 |
| RefSeq Protein Accession(s) | NP_001139117.1 |
| RefSeq mRNA Accession(s) | NM_001145645.2, NM_006573.4 |
| UniProt ID(s) | Q9Y275 |
| UniGene ID(s) | Hs.525157 |
| HGNC ID(s) | HGNC:11929 |
| COSMIC ID Link(s) | TNFSF13B |
| KEGG Gene ID(s) | hsa:10673 |
| PharmGKB ID(s) | PA434 |
| General Description of Recombinant Human BLyS / TNFSF13B / BAFF Protein . | |
| B cell-activating factor (BAFF), or B lymphocyte stimulator (BLyS), is a type II member of the tumor necrosis factor (TNF) superfamily. BAFF is expressed as a transmembrane protein on T cells, macrophages, and dendritic cells. The transmembrane domain of BAFF can also be cleaved to produce a soluble protein fragment. BAFF binds to the TNF receptors known as B cell maturation antigen (BCMA), transmembrane activator and CAML interactor (TACI), and BAFF receptor (BAFFR). BAFF is important for the survival and maturation of peripheral B cells. Human BAFF shows activity on mouse splenocytes. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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