PDF DatasheetHuman CCL11 / Eotaxin Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant CCL11 / Eotaxin based upon sequence from: Human
Host: QP5303 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Immunogen, Protein Standard, Other Cell Biology Applications
Application Notes: Please contact us for application specific information for QP5303.
Bioactivity Data: Untested
Monomer or Dimer: Monomer
Amino Acid Sequence: GPASVPTTCC FNLANRKIPL QRLESYRRIT SGKCPQKAVI FKTKLAKDIC ADPKKKWVQD SMKYLDQKSP TPKP
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human CCL11 / Eotaxin Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: Sterile filtered (0.22 um) solution containing 0.1% TFA
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.
| Recombinant Human CCL11 / Eotaxin Protein General Information | |
|---|---|
| Alternate Names | |
| CCL11, SCYA11 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CCL11 |
| Entrez Gene ID | 6356 |
| Ensemble Gene ID | ENSG00000172156 |
| RefSeq Protein Accession(s) | NP_002977.1 |
| RefSeq mRNA Accession(s) | NM_002986.2 |
| UniProt ID(s) | P51671 |
| UniGene ID(s) | Hs.54460 |
| HGNC ID(s) | HGNC:10610 |
| COSMIC ID Link(s) | CCL11 |
| KEGG Gene ID(s) | hsa:6356 |
| PharmGKB ID(s) | PA35543 |
| General Description of Recombinant Human CCL11 / Eotaxin Protein . | |
| Eotaxin-1, also known as Eotaxin and CCL11, is a chemokine that recruits eosinophils to sites of allergic inflammation. Eotaxin-1 signals through the G protein-coupled chemokine receptors CCR2, CCR3, and CCR5. Eotaxin-1 also negatively regulates adult neurogenesis, and high Eotaxin-1 levels are associated with impaired learning and memory. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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