PDF DatasheetHuman CCL11 / Eotaxin Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant CCL11 / Eotaxin based upon sequence from: Human
Host: QP10232 protein expressed in E. coli.
Tag: Untagged
Protein Construction: A DNA sequence encoding the Human CCL11 / Eotaxin, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP10232.
Bioactivity Data: Equivalent or superior bioactivity to competitors. Data available upon request. The biological activity determined by a chemotaxis bioassay using human peripheral blood eosinophils is in a concentration range of 0.1-10.0 ng/ml.
Full Length? Partial (see sequence information for more details).
Amino Acid Sequence: GPASVPTTCC FNLANRKIPL QRLESYRRIT SGKCPQKAVI FKTKLAKDIC ADPKKKWVQD SMKYLDQKSP TPKP
Purity: Greater than 97% as determined by SDS-PAGE and HPLC.
Reconstitution Instructions:
Concentration of Human CCL11 / Eotaxin Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than 1.0 EU/ug as determined by LAL method.
Buffer: 0.2 um filtered PBS, pH 7.4, lyophilized
Storage Conditions: Store at -20C to -80C.
| Recombinant Human CCL11 / Eotaxin Protein General Information | |
|---|---|
| Alternate Names | |
| CCL11; SCYA11 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CCL11 |
| Entrez Gene ID | 6356 |
| Ensemble Gene ID | ENSG00000172156 |
| RefSeq Protein Accession(s) | NP_002977.1 |
| RefSeq mRNA Accession(s) | NM_002986.2 |
| UniProt ID(s) | P51671 |
| UniGene ID(s) | Hs.54460 |
| HGNC ID(s) | HGNC:10610 |
| COSMIC ID Link(s) | CCL11 |
| KEGG Gene ID(s) | hsa:6356 |
| PharmGKB ID(s) | PA35543 |
| General Description of Recombinant Human CCL11 / Eotaxin Protein. | |
| In response to the presence of allergens, this protein directly promotes the accumulation of eosinophils, a prominent feature of allergic inflammatory reactions. Binds to CCR3. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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