PDF DatasheetHuman CCL4 / MIP1B Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant CCL4 / MIP1B based upon sequence from: Human
Host: QP5256 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Bioactive
Application Notes: Please contact us for application specific information for QP5256.
Bioactivity Data: Human CCL4 / MIP1B induces Human PBMC chemotaxis (significanty different from control at Human CCL4 / MIP1B concentrations greater than 3.1 ng/ml).
Monomer or Dimer: Monomer
Amino Acid Sequence: APMGSDPPTA CCFSYTARKL PHNFVVDYYE TSSLCSQPAV VFQTKRGKQV CADPSESWVQ EYVYDLELN
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human CCL4 / MIP1B Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: Sterile filtered (0.22 um) solution containing 0.1% TFA
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.
| Recombinant Human CCL4 / MIP1B Protein General Information | |
|---|---|
| Alternate Names | |
| CCL4, MIP1B, ACT2, HC21, MIP1B1, AT744.1, G-26, MIP1B, SCYA4, LAG1, LAG-1, MIP-1-beta, SCYA2 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CCL4 |
| Entrez Gene ID | 388372 |
| Ensemble Gene ID | ENSG00000275302 |
| RefSeq Protein Accession(s) | NP_002975.1 |
| RefSeq mRNA Accession(s) | NM_002984.3, NM_207007.3 |
| UniProt ID(s) | P13236 |
| UniGene ID(s) | Hs.449862 |
| HGNC ID(s) | HGNC:10630 |
| KEGG Gene ID(s) | hsa:388372 |
| PharmGKB ID(s) | PA35563 |
| General Description of Recombinant Human CCL4 / MIP1B Protein . | |
| Macrophage inflammatory protein-1 beta (MIP-1-beta), also known as CCL4, is produced by macrophages and functions as a mitogen-inducible cytokine. MIP-1-beta signals through the chemokine receptor CCR5 to chemoattract immune cells. MIP-1-beta induces inflammatory responses, including neutrophil superoxide production. The MIP-1-alpha and MIP-1-beta heterodimer exhibits antiviral activity against the human immunodeficiency virus 1 (HIV-1). | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
There are no reviews yet.