PDF DatasheetHuman EG-VEGF / prokineticin-1 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant EG-VEGF / prokineticin-1 based upon sequence from: Human
Host: QP5230 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Immunogen, Protein Standard, Other Cell Biology Applications
Application Notes: Please contact us for application specific information for QP5230.
Bioactivity Data: Untested
Monomer or Dimer: Monomer
Amino Acid Sequence: AVITGACERD VQCGAGTCC A ISLWLRGL RM CTPLGRE GEE CHPGSH KVPF FRKRK HHTCP CLPN LLCSRF PDG RYRCSMD LK NINF
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human EG-VEGF / prokineticin-1 Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: Sterile filtered (0.22 um) solution containing 0.1% TFA
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.
| Recombinant Human EG-VEGF / prokineticin-1 Protein General Information | |
|---|---|
| Alternate Names | |
| EG-VEGF, prokineticin-1, PK1, EGVEGF, PRK1 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | PROK1 |
| Entrez Gene ID | 84432 |
| Ensemble Gene ID | ENSG00000143125 |
| RefSeq Protein Accession(s) | NP_115790.1 |
| RefSeq mRNA Accession(s) | NM_032414.2 |
| UniProt ID(s) | P58294 |
| UniGene ID(s) | Hs.514793 |
| HGNC ID(s) | HGNC:18454 |
| COSMIC ID Link(s) | PROK1 |
| KEGG Gene ID(s) | hsa:84432 |
| PharmGKB ID(s) | PA38539 |
| General Description of Recombinant Human EG-VEGF / prokineticin-1 Protein . | |
| Endocrine gland-derived vascular endothelial growth factor (EG-VEGF) is an angiogenic growth factor that is expressed in the ovaries, testis, adrenal, and placental tissues. EG-VEGF has mitogenic, chemoattractive, and antiapoptotic functional roles. EG-VEGF signaling is mediated through binding the G protein-coupled receptors prokineticin receptor 1 (PKR1) and prokineticin receptor 2 (PKR2). Polycystic ovaries display strong EG-VEGF expression that is associated with increased angiogenesis and cyst formation, which could lead to the formation of polycystic ovary syndrome and infertility. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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