PDF DatasheetHuman EG-VEGF / prokineticin-1 Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant EG-VEGF / prokineticin-1 based upon sequence from: Human
Host: QP10402 protein expressed in E. coli.
Tag: Untagged
Protein Construction: A DNA sequence encoding the Human EG-VEGF / prokineticin-1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP10402.
Bioactivity Data: Equivalent or superior bioactivity to competitors. Data available upon request. The ED50 as determined by a cell proliferation assay using bovine EJG cells is less than 2.0 ug/ml, corresponding to a specific activity of > 500 IU/mg.
Full Length? Partial (see sequence information for more details).
Amino Acid Sequence: AVITGACERD VQCGAGTCCA ISLWLRGLRM CTPLGREGEE CHPGSHKVPF FRKRKHHTCP CLPNLLCSRF PDGRYRCSMD LKNINF
Purity: Greater than 98% as determined by SDS-PAGE and HPLC.
Reconstitution Instructions:
Concentration of Human EG-VEGF / prokineticin-1 Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than 1.0 EU/ug as determined by LAL method.
Buffer: 0.2 um filtered PBS, pH 7.4, 0.02 % Tween-20, lyophilized
Storage Conditions: Store at -20C to -80C.
| Recombinant Human EG-VEGF / prokineticin-1 Protein General Information | |
|---|---|
| Alternate Names | |
| EG-VEGF; prokineticin-1; PK1; EGVEGF; PRK1 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | PROK1 |
| Entrez Gene ID | 84432 |
| Ensemble Gene ID | ENSG00000143125 |
| RefSeq Protein Accession(s) | NP_115790.1 |
| RefSeq mRNA Accession(s) | NM_032414.2 |
| UniProt ID(s) | P58294 |
| UniGene ID(s) | Hs.514793 |
| HGNC ID(s) | HGNC:18454 |
| COSMIC ID Link(s) | PROK1 |
| KEGG Gene ID(s) | hsa:84432 |
| PharmGKB ID(s) | PA38539 |
| General Description of Recombinant Human EG-VEGF / prokineticin-1 Protein. | |
| Potently contracts gastrointestinal (GI) smooth muscle. Induces proliferation, migration and fenestration (the formation of membrane discontinuities) in capillary endothelial cells derived from endocrine glands. Has little or no effect on a variety of other endothelial and non-endothelial cell types. Induces proliferation and differentiation, but not migration, of enteric neural crest cells. Directly influences neuroblastoma progression by promoting the proliferation and migration of neuroblastoma cells. Positively regulates PTGS2 expression and prostaglandin synthesis. May play a role in placentation. May play a role in normal and pathological testis angiogenesis. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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