PDF DatasheetHuman FGF21 / Fibroblast Growth Factor 21 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant FGF21 / Fibroblast Growth Factor 21 based upon sequence from: Human
Host: QP5272 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Immunogen, Protein Standard, Other Cell Biology Applications
Application Notes: Please contact us for application specific information for QP5272.
Bioactivity Data: Untested
Monomer or Dimer: Monomer
Amino Acid Sequence: MHPIPDSSPL LQFGGQVRQ R YLYTDDAQ QT EAHLEIR EDG TVGGAA DQSP ESLLQ LKALK PGVI QILGVK TSR FLCQRPD GA LYGSLHFD P EACSFRELLL EDGYNVYQS EAHGLPLHLP GNKSPHRDP A PRGPARFL PL PGLPPAL PEP PGILAP QPPD VGSSD PLSMV GPSQ GRSPSY AS
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human FGF21 / Fibroblast Growth Factor 21 Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: 10 mM sodium phosphate, 100 mM soldium chloride, pH 7.5
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.
| Recombinant Human FGF21 / Fibroblast Growth Factor 21 Protein General Information | |
|---|---|
| Alternate Names | |
| FGF21, Fibroblast Growth Factor 21 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | FGF21 |
| Entrez Gene ID | 26291 |
| Ensemble Gene ID | ENSG00000105550 |
| RefSeq Protein Accession(s) | NP_061986.1 |
| RefSeq mRNA Accession(s) | NM_019113.3 |
| UniProt ID(s) | Q9NSA1 |
| UniGene ID(s) | Hs.283015 |
| HGNC ID(s) | HGNC:3678 |
| COSMIC ID Link(s) | FGF21 |
| KEGG Gene ID(s) | hsa:26291 |
| PharmGKB ID(s) | PA28117 |
| General Description of Recombinant Human FGF21 / Fibroblast Growth Factor 21 Protein . | |
| Fibroblast growth factor 21 (FGF21) is an endocrine hormone that regulates energy homeostasis and exerts cardioprotective functions during heart injury. FGF21 is expressed in the liver, pancreas, heart, and adipose tissues. FGF21 signaling is activated through the FGFR1c receptor and ?-Klotho co-receptor. FGF21 is an important regulator of glucose uptake and reduces cell apoptosis under stress conditions. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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