PDF DatasheetHuman FGF8 Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant FGF8 based upon sequence from: Human
Host: QP5301 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Bioactive
Application Notes: Please contact us for application specific information for QP5301.
Bioactivity Data: At minimum, our recombinant Human FGF8 induces 3T3 cell proliferation at concentrations of less than 150 ng/ml (activity must be at least 6.7 x 10^3 units/mg).
Monomer or Dimer: Monomer
Amino Acid Sequence: MQVTVQSSPN FTQHVREQS L VTDQLSRR LI RTYQLYS RTS GKHVQV LANK RINAM AEDGD PFAK LIVETD TFG SRVRVRGAET GLYICMN KK GKLIAKSN G KGKDCVFTE IVLENNYTAL QNAKYEGWY M AFTRKGRP RK GSKTRQH QRE VHFMKR LPRG HHTTE QSLRFEFLNY PPFTR SLRG SQRTWA PEP R
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human FGF8 Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: 5 mM sodium phosphate, 50mM soldium chloride, pH 7.5
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.
| Recombinant Human FGF8 Protein General Information | |
|---|---|
| Alternate Names | |
| FGF8, FGF-8 Protein, AIGF, FGF-8, KAL6, HBGF-8, HH6 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | FGF8 |
| Entrez Gene ID | 2253 |
| Ensemble Gene ID | ENSG00000107831 |
| RefSeq Protein Accession(s) | NP_006110.1 |
| RefSeq mRNA Accession(s) | NM_006119.4, NM_033163.3, NM_033164.3, NM_033165.3 |
| UniProt ID(s) | P55075 |
| UniGene ID(s) | Hs.57710 |
| HGNC ID(s) | HGNC:3686 |
| COSMIC ID Link(s) | FGF8 |
| KEGG Gene ID(s) | hsa:2253 |
| PharmGKB ID(s) | PA28125 |
| General Description of Recombinant Human FGF8 Protein . | |
| Fibroblast growth factor 8 (FGF8) is a critical mitogenic factor that is required for normal development of the eye, ear, brain, and limb. FGF8 broadly functions to promote cell proliferation, differentiation, and migration. Overexpression of FGF8 increases tumor growth and angiogenesis. Human and mouse FGF8 proteins show 100% homology. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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