PDF DatasheetMouse Fgf8 Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant Fgf8 based upon sequence from Mouse
Host: QP5478 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Bioactive
Application Notes: Please contact us for application specific information for QP5478.
Bioactivity Data: 3T3 cell proliferation significantly induced by less than 150 ng/ml of Mouse Fgf8 (typical ED50 is ? 20 ng/ml).
Monomer or Dimer: Monomer
Amino Acid Sequence: MQVTVQSSPN FTQHVREQS L VTDQLSRR LI RTYQLYS RTS GKHVQV LANK RINAM AEDGD PFAK LIVETD TFG SRVRVRGAET GLYICMN KK GKLIAKSN G KGKDCVFTE IVLENNYTAL QNAKYEGWY M AFTRKGRP RK GSKTRQH QRE VHFMKR LPRG HHTTE QSLRFEFLNY PPFTR SLRG SQRTWA PEP R
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions: A Certificate of Analysis (CofA) will be sent along with the protein and will contain the proper reconstitution instructions.
Concentration of Mouse Fgf8 Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: 10 mM sodium phosphate, 50 mM sodium chloride, pH 7.5
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.
| Recombinant Mouse Fgf8 Protein General Information | |
|---|---|
| Alternate Names | |
| FGF8, FGF-8 Protein, AIGF, FGF-8, KAL6, HBGF-8, HH6 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | FGF8 |
| Entrez Gene ID | 14179 |
| Ensemble Gene ID | ENSMUSG00000025219 |
| RefSeq Protein Accession(s) | NP_001159834.1 |
| RefSeq mRNA Accession(s) | NM_001166362.1, NM_001166363.1, NM_010205.2 |
| UniProt ID(s) | P37237 |
| UniGene ID(s) | Mm.4012 |
| COSMIC ID Link(s) | FGF8 |
| KEGG Gene ID(s) | mmu:14179 |
| General Description of Recombinant Mouse Fgf8 Protein . | |
| Fibroblast growth factor 8 (FGF8) is a critical mitogenic factor that is required for normal development of the eye, ear, brain, and limb. FGF8 broadly functions to promote cell proliferation, differentiation, and migration. Overexpression of FGF8 increases tumor growth and angiogenesis. Human and mouse FGF8 proteins show 100% homology. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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