PDF DatasheetHuman IFNG / Interferon Gamma Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant IFNG / Interferon Gamma based upon sequence from: Human
Host: QP5378 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Bioactive
Application Notes: Please contact us for application specific information for QP5378.
Bioactivity Data: BioActivity: Shows bioactivity in the Viral CPE assay using EMC virus on A549 cells assay. The bioactivity acceptance criteria is set at 1.0 x 10^7 units/mg.
Monomer or Dimer: Monomer
Amino Acid Sequence: MQDPYVKEAE NLKKYFNAGH SDVADNGTLF LGILKNWKEE SDRKIMQSQI VSFYFKLFKN FKDDQSIQKS VETIKEDMNV KFFNSNKKKR DDFEKLTNYS VTDLNVQRKA IHELIQVMAE LSPAAKTGKR KRSQMLFQGR RASQ
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human IFNG / Interferon Gamma Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: 10 mM sodium phosphate, 50 mM sodium chloride, pH 7.5
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.
| Recombinant Human IFNG / Interferon Gamma Protein General Information | |
|---|---|
| Alternate Names | |
| IFNG, Interferon Gamma Protein, EGK_03901, IFN-gamma | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | IFNG |
| Entrez Gene ID | 3458 |
| Ensemble Gene ID | ENSG00000111537 |
| RefSeq Protein Accession(s) | NP_000610.2 |
| RefSeq mRNA Accession(s) | NM_000619.2 |
| UniProt ID(s) | P01579 |
| UniGene ID(s) | Hs.856 |
| HGNC ID(s) | HGNC:5438 |
| COSMIC ID Link(s) | IFNG |
| KEGG Gene ID(s) | hsa:3458 |
| PharmGKB ID(s) | PA29674 |
| General Description of Recombinant Human IFNG / Interferon Gamma Protein. | |
| Interferon gamma (IFN?) is a type II interferon that is critical during adaptive and innate immune responses to infection. IFN? is produced by T cells and natural killer cells following antigen-specific activation. IFN? binds IFN? receptors (IFN?R1 and IFN?R2), which are expressed on most immune cells, to activate the JAK-STAT pathway. IFN?-induced signaling increases the expression of class 1 major histocompatibility complex (MHC) molecules. Human IFN? is not cross-reactive with mouse IFN?. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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