Mouse IFNG / Interferon Gamma Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant IFNG / Interferon Gamma based upon sequence from: Mouse
Host: QP4141 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Bioactive
Application Notes: Please contact us for application specific information for QP4141.
Bioactivity Data: BioActivity: Shows bioactivity in the Viral CPE assay using EMC virus on L929 cells assay. The bioactivity acceptance criteria is set at 1 x 10^7 units/mg.
Monomer or Dimer: Monomer
Amino Acid Sequence: MHGTVIESLE SLNNYFNSSG IDVEEKSLFL DIWRNWQKDG DMKILQSQII SFYLRLFEVL KDNQAISNNI SVIESHLITT FFSNSKAKKD AFMSIAKFEV NNPQVQRQAF NELIRVVHQL LPESSLRKRK RSRC
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Mouse IFNG / Interferon Gamma Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: 10 mM sodium phosphate, 100 mM sodium chloride, pH 7.5
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.
Recombinant Mouse IFNG / Interferon Gamma Protein General Information | |
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Alternate Names | |
IFNG, Interferon Gamma Protein, EGK_03901, IFN-gamma | |
Curated Database and Bioinformatic Data | |
Gene Symbol | IFNG |
Entrez Gene ID | 15978 |
Ensemble Gene ID | ENSMUSG00000055170 |
RefSeq Protein Accession(s) | NP_032363.1 |
RefSeq mRNA Accession(s) | NM_008337.4 |
UniProt ID(s) | P01580 |
UniGene ID(s) | Mm.240327 |
COSMIC ID Link(s) | IFNG |
KEGG Gene ID(s) | mmu:15978 |
General Description of Recombinant Mouse IFNG / Interferon Gamma Protein. | |
Interferon gamma (IFN?) is a type II interferon that is critical during adaptive and innate immune responses to infection. IFN? is produced by T cells and natural killer cells following antigen-specific activation. IFN? binds IFN? receptors (IFN?R1 and IFN?R2), which are expressed on most immune cells, to activate the JAK-STAT pathway. IFN?-induced signaling increases the expression of class 1 major histocompatibility complex (MHC) molecules. Mouse IFN? is not cross-reactive with human IFN?. |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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