PDF DatasheetHuman IGF-2 / IGF-II Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant IGF-2 / IGF-II based upon sequence from: Human
Host: QP5264 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Bioactive
Application Notes: Please contact us for application specific information for QP5264.
Bioactivity Data: BioActivity: Shows bioactivity at a concentration of 15 ng/mL in the Mouse FDC-P1 cell proliferation assay. The bioactivity acceptance criteria is set at 6.7 x 10^4 units/mg.
Monomer or Dimer: Monomer
Amino Acid Sequence: AYRPSETLCG GELVDTLQFV CGDRGFYFSR PASRVSRRSR GIVEECCFRS CDLALLETYC ATPAKSE
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human IGF-2 / IGF-II Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: Sterile filtered (0.22 um) solution containing 0.1% TFA
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.
| Recombinant Human IGF-2 / IGF-II Protein General Information | |
|---|---|
| Alternate Names | |
| IGF-2, IGF-II, IGF-II, C11orf43, GRDF, PP9974 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | IGF2 |
| Entrez Gene ID | 3481 |
| Ensemble Gene ID | ENSG00000167244 |
| RefSeq Protein Accession(s) | NP_000603.1 |
| RefSeq mRNA Accession(s) | NM_000612.5, NM_001007139.5, NM_001127598.2, NM_001291861.2, NM_001291862.2 |
| UniProt ID(s) | P01344 |
| UniGene ID(s) | Hs.272259 |
| HGNC ID(s) | HGNC:5466 |
| COSMIC ID Link(s) | IGF2 |
| KEGG Gene ID(s) | hsa:3481 |
| PharmGKB ID(s) | PA29699 |
| General Description of Recombinant Human IGF-2 / IGF-II Protein. | |
| Insulin-like growth factor II (IGF-II) is an important fetal growth hormone made by theca cells during gestation. IGF-II engages the IGF-I receptor (IGF1R) to mediate embryonic growth. IGF-II also binds the sink IGF-II receptor (IGF2R) leading to IGF-II degradation. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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