PDF DatasheetHuman IL-8 / CXCL8 Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant IL-8 / CXCL8 based upon sequence from: Human
Host: QP2737 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Bioactive
Application Notes: Please contact us for application specific information for QP2737.
Bioactivity Data: Human IL-8 / CXCL8 induces Human neutrophil chemotaxis (significanty different from control at Human IL-8 / CXCL8 concentrations greater than 10 ng/ml) Activity was further confirmed by measuring Human neutrophil degranulation (significanty different from control at Human IL-8 / CXCL8 concentrations greater than 1 ng/ml)
Monomer or Dimer: Monomer
Amino Acid Sequence: AVLPRSAKEL RCQCIKTYS K PFHPKFIK EL RVIESGP HCA NTEIIV KLSD GRELC LDPKE NWVQ RVVEKF LKR AENS
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human IL-8 / CXCL8 Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: 10 mM sodium phosphate, pH 7.5
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.
| Recombinant Human IL-8 / CXCL8 Protein General Information | |
|---|---|
| Alternate Names | |
| IL-8, CXCL8, GCP-1, MDNCF, NAP1, GCP1, IL8, NAF, MONAP, LECT, LYNAP, NAP-1, LUCT | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CXCL8 |
| Entrez Gene ID | 3576 |
| Ensemble Gene ID | ENSG00000169429 |
| RefSeq Protein Accession(s) | NP_000575.1 |
| RefSeq mRNA Accession(s) | NM_000584.3 |
| UniProt ID(s) | P10145 |
| UniGene ID(s) | Hs.624 |
| HGNC ID(s) | HGNC:6025 |
| KEGG Gene ID(s) | hsa:3576 |
| PharmGKB ID(s) | PA29841 |
| General Description of Recombinant Human IL-8 / CXCL8 Protein . | |
| Interleukin 8 (IL-8 or CXCL8) is a member of the CXC cytokine family and is produced by macrophages, epithelial, smooth muscle, and endothelial cells. IL-8 binds the G protein-coupled serpentine receptors CXCR1 and CXCR2. IL-8 recruits innate immune cells, induces phagocytosis, and stimulate angiogenesis. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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