PDF DatasheetHuman IL19 / Interleukin-19 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant IL19 / Interleukin-19 based upon sequence from: Human
Host: QP5391 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Immunogen, Protein Standard, Other Cell Biology Applications
Application Notes: Please contact us for application specific information for QP5391.
Bioactivity Data: Untested
Monomer or Dimer: Monomer
Amino Acid Sequence: MLRRCLISTD MHHIEESFQE IKRAIQAKDT FPNVTILSTL ETLQIIKPLD VCCVTKNLLA FYVDRVFKDH QEPNPKILRK ISSIANSFLY MQKTLRQCQE QRQCHCRQEA TNATRVIHDN YDQLEVHAAA IKSLGELDVF LAWINKNHEV MFSA
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human IL19 / Interleukin-19 Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: Sterile filtered (0.22 um) solution containing 0.1% TFA
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.
| Recombinant Human IL19 / Interleukin-19 Protein General Information | |
|---|---|
| Alternate Names | |
| IL19, Interleukin-19, NG.1, ZMDA1, MDA1, IL-10C | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | IL19 |
| Entrez Gene ID | 29949 |
| Ensemble Gene ID | ENSG00000142224 |
| RefSeq Protein Accession(s) | NP_037503.2 |
| RefSeq mRNA Accession(s) | NM_013371.3, NM_153758.2, XM_011509450.2 |
| UniProt ID(s) | Q9UHD0 |
| UniGene ID(s) | Hs.661017 |
| HGNC ID(s) | HGNC:5990 |
| COSMIC ID Link(s) | IL19 |
| KEGG Gene ID(s) | hsa:29949 |
| PharmGKB ID(s) | PA29806 |
| General Description of Recombinant Human IL19 / Interleukin-19 Protein . | |
| Interleukin-19 (IL-19) is a member of the interleukin 10 (IL-10) cytokine family and is produced by B cells and monocytes. IL-19 binds the interleukin 20 receptor complex (IL-20R) to activate STAT3 signaling. IL-19 induces interleukin 6 (IL-6) and tumor necrosis factor alpha (TNF-a) expression in monocytes, and promotes T helper 2 (Th2) cell-mediated immune responses. IL-19 production is up-regulated in resting monocytes following granulocyte-macrophage colony-stimulating factor (GM-CSF) or lipopolysaccharide (LPS) stimulation. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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