PDF DatasheetHuman IL19 / Interleukin-19 Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant IL19 / Interleukin-19 based upon sequence from: Human
Host: QP10324 protein expressed in E. coli.
Tag: Untagged
Protein Construction: A DNA sequence encoding the Human IL19 / Interleukin-19, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP10324.
Bioactivity Data: Equivalent or superior bioactivity to competitors. Data available upon request. The ED50 as determined by a cell proliferation assay using human IL-20Ralpha and human IL-20Rbeta co-transfected murine BaF3 pro-B cells is less than 1.5 ng/ml, corresponding to a specific activity of > 6.7×105 IU/mg.
Full Length? Partial (see sequence information for more details).
Amino Acid Sequence: LRRCLISTDM HHIEESFQEI KRAIQAKDTF PNVTILSTLE TLQIIKPLDV CCVTKNLLAF YVDRVFKDHQ EPNPKILRKI SSIANSFLYM QKTLRQCQEQ RQCHCRQEAT NATRVIHDNY DQLEVHAAAI KSLGELDVFL AWINKNHEVM SSA
Purity: Greater than 95% as determined by SDS-PAGE and HPLC.
Reconstitution Instructions:
Concentration of Human IL19 / Interleukin-19 Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than 1.0 EU/ug as determined by LAL method.
Buffer: 0.2 um filtered PBS, pH 7.4, lyophilized
Storage Conditions: Store at -20C to -80C.
| Recombinant Human IL19 / Interleukin-19 Protein General Information | |
|---|---|
| Alternate Names | |
| IL19; Interleukin-19; NG.1; ZMDA1; MDA1; IL-10C | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | IL19 |
| Entrez Gene ID | 29949 |
| Ensemble Gene ID | ENSG00000142224 |
| RefSeq Protein Accession(s) | NP_037503.2 |
| RefSeq mRNA Accession(s) | NM_013371.3, NM_153758.2, XM_011509450.2 |
| UniProt ID(s) | Q9UHD0 |
| UniGene ID(s) | Hs.661017 |
| HGNC ID(s) | HGNC:5990 |
| COSMIC ID Link(s) | IL19 |
| KEGG Gene ID(s) | hsa:29949 |
| PharmGKB ID(s) | PA29806 |
| General Description of Recombinant Human IL19 / Interleukin-19 Protein. | |
| May play some important roles in inflammatory responses. Up-regulates IL-6 and TNF-alpha and induces apoptosis (By similarity). | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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