PDF DatasheetHuman IL-3 / Interleukin-3 Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant IL-3 / Interleukin-3 based upon sequence from Human
Host: QP1167 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Bioactive
Application Notes: Please contact us for application specific information for QP1167.
Bioactivity Data: BioActivity: Shows bioactivity at a concentration of 2 ng/mL in the TF-1 cell proliferation assay. The bioactivity acceptance criteria is set at 5.0 x 10^5 units/mg.
Monomer or Dimer: Monomer
Amino Acid Sequence: MAPMTQTTPL KTSWVNCSNM IDEIITHLKQ PPLPLLDFNN LNGEDQDILM ENNLRRPNLE AFNRAVKSLQ NASAIESILK NLLPCLPLAT AAPTRHPIHI KDGDWNEFRR KLTFYLKTLE NAQAQQTTLS LAIF
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions: A Certificate of Analysis (CofA) will be sent along with the protein and will contain the proper reconstitution instructions.
Concentration of Human IL-3 / Interleukin-3 Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: Sterile filtered (0.22 um) solution containing 0.1% TFA
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.
| Recombinant Human IL-3 / Interleukin-3 Protein General Information | |
|---|---|
| Alternate Names | |
| IL-3, Interleukin-3, BPA, Csfmu, Il-3, PSF, HCGF, MCGF | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | IL3 |
| Entrez Gene ID | 3562 |
| Ensemble Gene ID | ENSG00000164399 |
| RefSeq Protein Accession(s) | NP_000579.2 |
| RefSeq mRNA Accession(s) | NM_000588.3 |
| UniProt ID(s) | P08700 |
| UniGene ID(s) | Hs.694 |
| HGNC ID(s) | HGNC:6011 |
| COSMIC ID Link(s) | IL3 |
| KEGG Gene ID(s) | hsa:3562 |
| PharmGKB ID(s) | PA29830 |
| General Description of Recombinant Human IL-3 / Interleukin-3 Protein. | |
| Interleukin 3 (IL-3) is a cytokine that is produced by activated T cells and mast cells. IL-3 induces the differentiation of hematopoietic stem cells into myeloid precursor cells, such as erythrocyte, megakaryocyte, granulocyte, monocyte, and dendritic cells. IL-3 also functions in the nervous system and is important during the B-1 cell regulation of chronic inflammatory diseases. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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