PDF DatasheetMacaque IL-3 / Interleukin-3 Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant IL-3 / Interleukin-3 based upon sequence from: Macaque
Host: QP10336 protein expressed in E. coli.
Tag: Untagged
Protein Construction: A DNA sequence encoding the Rhesus Macaque IL-3 / Interleukin-3, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP10336.
Bioactivity Data: Assay #1: Equivalent or superior bioactivity to competitors. Data available upon request. The ED50 as determined by the dose- dependent stimulation of the proliferation of murine NFS-60 cells is less than 5.0 ng/ml, corresponding to a specific activity of > 2 × 105 IU/mg. Assay #2: The ED50 as determined by a cell proliferation assay using human TF-1 cells is less than 0.05 ng/ml, corresponding to a specific activity of > 2.0 × 107 IU/mg.
Full Length? Partial (see sequence information for more details).
Amino Acid Sequence: APMTQTTSLK TSWAKCSNMI DEIITHLNQP PLPSPDFNNL NEEDQTILVE KNLRRSNLEA FSKAVKSLQN ASAIESILKN LPPCLPMATA APTRPPIRIT NGDRNDFRRK LKFYLKTLEN EQAQ
Purity: Greater than 98% as determined by SDS-PAGE and HPLC.
Reconstitution Instructions:
Concentration of Macaque IL-3 / Interleukin-3 Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than 1.0 EU/ug as determined by LAL method.
Buffer: 0.2 um filtered PBS, pH 7.4, 5 % trehalose, lyophilized
Storage Conditions: Store at -20C to -80C.
| Recombinant Macaque IL-3 / Interleukin-3 Protein General Information | |
|---|---|
| Curated Database and Bioinformatic Data | |
| Gene Symbol | IL3 |
| Entrez Gene ID | 706946 |
| Ensemble Gene ID | ENSMMUG00000016912 |
| RefSeq Protein Accession(s) | NP_001095204.1 |
| RefSeq mRNA Accession(s) | NM_001101734.1 |
| UniProt ID(s) | P25140 |
| COSMIC ID Link(s) | IL3 |
| KEGG Gene ID(s) | mcc:706946 |
| General Description of Recombinant Macaque IL-3 / Interleukin-3 Protein. | |
| Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages.; This CSF induces granulocytes, macrophages, mast cells, stem cells, erythroid cells, eosinophils and megakaryocytes. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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