PDF DatasheetHuman NTF3 / Neurotrophin 3 Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant NTF3 / Neurotrophin 3 based upon sequence from Human
Host: QP1246 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Bioactive
Application Notes: Please contact us for application specific information for QP1246.
Bioactivity Data: BioActivity: Shows bioactivity at a concentration of 20 ug/mL in the C6 cell proliferation assay. The bioactivity acceptance criteria is set at 50 units/mg.
Monomer or Dimer: Dimer (non-covalently linked)
Amino Acid Sequence: MYAEHKSHRG EYSVCDSESL WVTDKSSAID IRGHQVTVLG EIKTGNSPVK QYFYETRCKE ARPVKNGCRG IDDKHWNSQC KTSQTYVRAL TSENNKLVGW RWIRIDTSCV CALSRKIGRT
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions: A Certificate of Analysis (CofA) will be sent along with the protein and will contain the proper reconstitution instructions.
Concentration of Human NTF3 / Neurotrophin 3 Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: Sterile filtered (0.22 um) solution containing 0.1% TFA
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.
| Recombinant Human NTF3 / Neurotrophin 3 Protein General Information | |
|---|---|
| Alternate Names | |
| NTF3, Neurotrophin 3 Protein, NT-3, NGF-2, HDNF, NT3, NGF2 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | NTF3 |
| Entrez Gene ID | 4908 |
| Ensemble Gene ID | ENSG00000185652 |
| RefSeq Protein Accession(s) | NP_001096124.1 |
| RefSeq mRNA Accession(s) | NM_001102654.1, NM_002527.4, XM_011520963.2 |
| UniProt ID(s) | P20783 |
| UniGene ID(s) | Hs.99171 |
| HGNC ID(s) | HGNC:8023 |
| COSMIC ID Link(s) | NTF3 |
| KEGG Gene ID(s) | hsa:4908 |
| PharmGKB ID(s) | PA31806 |
| General Description of Recombinant Human NTF3 / Neurotrophin 3 Protein. | |
| Neurotrophin-3 (NT-3) is an important member of the nerve growth factor (NGF) family of proteins. NT-3 promotes the growth, survival, and differentiation of neurons and synapses in the peripheral and central nervous systems. The receptor tyrosine kinase TrkC exclusively binds in high-affinity to NT-3. NT-3 also signals through the receptor tyrosine kinase TrkB, and through the low affinity nerve growth factor receptor (LNGFR). | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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