Mouse NTF3 / Neurotrophin 3 Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant NTF3 / Neurotrophin 3 based upon sequence from: Mouse
Host: QP5425 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Bioactive
Application Notes: Please contact us for application specific information for QP5425.
Bioactivity Data: Mouse NTF3 / Neurotrophin 3 induces Rat C6 cell proliferation.
Monomer or Dimer: Dimer
Amino Acid Sequence: MYAEHKSHRG EYSVCDSESL WVTDKSSAID IRGHQVTVLG EIKTGNSPVK QYFYETRCKE ARPVKNGCRG IDDKHWNSQC KTSQTYVRAL TSENNKLVGW RWIRIDTSCV CALSRKIGRT
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Mouse NTF3 / Neurotrophin 3 Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: Sterile filtered (0.22 um) solution containing 0.1% TFA
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.
Recombinant Mouse NTF3 / Neurotrophin 3 Protein General Information | |
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Alternate Names | |
NTF3, Neurotrophin 3 Protein, NT-3, NGF-2, HDNF, NT3, NGF2 | |
Curated Database and Bioinformatic Data | |
Gene Symbol | NTF3 |
Entrez Gene ID | 18205 |
Ensemble Gene ID | ENSMUSG00000049107 |
RefSeq Protein Accession(s) | NP_001157506.1 |
RefSeq mRNA Accession(s) | NM_001164034.1, NM_001164035.1, NM_008742.3, XM_006505716.2 |
UniProt ID(s) | P20181 |
UniGene ID(s) | Mm.267570 |
COSMIC ID Link(s) | NTF3 |
KEGG Gene ID(s) | mmu:18205 |
General Description of Recombinant Mouse NTF3 / Neurotrophin 3 Protein . | |
Neurotrophin-3 (NT-3) is an important member of the nerve growth factor (NGF) family of proteins. NT-3 promotes the growth, survival, and differentiation of neurons and synapses in the peripheral and central nervous systems. The receptor tyrosine kinase TrkC exclusively binds in high-affinity to NT-3. NT-3 also signals through the receptor tyrosine kinase TrkB, and through the low affinity nerve growth factor receptor (LNGFR). |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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