PDF DatasheetHuman TNFR1 / CD120a / TNFRSF1A Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant TNFR1 / CD120a / TNFRSF1A based upon sequence from: Human
Host: QP5348 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Bioactive
Application Notes: Please contact us for application specific information for QP5348.
Bioactivity Data: Neutralization of human TNF alpha induced L929 cell cytolysis significantly was induced by less than 100 ng/ml of Human TNFR1 / CD120a / TNFRSF1A which corresponds to an activity of at least 1.0 x 10^4 units/mg.
Monomer or Dimer: Monomer
Amino Acid Sequence: MDSVCPQGKY IHPQNNSICC TKCHKGTYLY NDCPGPGQDT DCRECESGSF TASENHLRHC LSCSKCRKEM GQVEISSCTV DRDTVCGCKN QYRHYWSENL FQCFNCSLCL NGTVHLSCQE KQNTVCTCHA GFFLRENECV SCSNCKKSLE CTKLCLPQIE N
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human TNFR1 / CD120a / TNFRSF1A Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: 10 mM sodium phosphate, pH 7.5
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.
| Recombinant Human TNFR1 / CD120a / TNFRSF1A Protein General Information | |
|---|---|
| Alternate Names | |
| TNFR1, CD120a, TNFRSF1A, TNF-R55, TNF-alphaR1, Tnfr1, p55-R, FPF, TNFRp55, TNF-R, TNF-R-I, TNF-R1, TNFAR, TNFR60, TNFalpha-R1, Tnfr-2, p55, CD120a, TNFRI | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | TNFRSF1A |
| Entrez Gene ID | 7132 |
| Ensemble Gene ID | ENSG00000067182 |
| RefSeq Protein Accession(s) | NP_001056.1 |
| RefSeq mRNA Accession(s) | NM_001065.3, NM_001346091.1, NM_001346092.1 |
| UniProt ID(s) | P19438 |
| UniGene ID(s) | Hs.279594 |
| HGNC ID(s) | HGNC:11916 |
| COSMIC ID Link(s) | TNFRSF1A |
| KEGG Gene ID(s) | hsa:7132 |
| PharmGKB ID(s) | PA36609 |
| General Description of Recombinant Human TNFR1 / CD120a / TNFRSF1A Protein . | |
| Tumor necrosis factor receptor type 1 (TNFR1) is expressed in most tissues and is activated by soluble and membrane-bound tumor necrosis factor alpha (TNFa). TNFR1 activates NF-?B and MAPK pathways to induce inflammation, promote apoptotic cell death, inhibit tumorigenesis, and inhibit viral replication. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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