Mouse beta-NGF / Beta-NGF Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant beta-NGF / Beta-NGF based upon sequence from: Mouse
Host: QP5412 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Immunogen, Protein Standard, Other Cell Biology Applications
Application Notes: Please contact us for application specific information for QP5412.
Bioactivity Data: Untested
Monomer or Dimer: Dimer
Amino Acid Sequence: MSSTHPVFHM GEFSVCDSVS VWVGDKTTAT DIKGKEVTVL AEVNINNSVF RQYFFETKCR ASNPVESGCR GIDSKHWNSY CTTTHTFVKA LTTDEKQAAW RFIRIDTACV CVLSRKATRR G
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Mouse beta-NGF / Beta-NGF Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: Sterile filtered (0.22 um) solution containing 0.1% TFA
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.
Recombinant Mouse beta-NGF / Beta-NGF Protein General Information | |
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Alternate Names | |
beta-NGF, Beta-NGF Protein, HSAN5, Beta-NGF, NGFB | |
Curated Database and Bioinformatic Data | |
Gene Symbol | NGF |
Entrez Gene ID | 18049 |
Ensemble Gene ID | ENSMUSG00000027859 |
RefSeq Protein Accession(s) | NP_038637.1 |
RefSeq mRNA Accession(s) | NM_013609.3, XM_006501108.3 |
UniProt ID(s) | Q6LDU8 |
UniGene ID(s) | Mm.1259 |
COSMIC ID Link(s) | NGF |
General Description of Recombinant Mouse beta-NGF / Beta-NGF Protein . | |
Nerve growth factor beta (beta-NGF) is a neurotrophic factor that is important for the development and maintenance of sensory and sympathetic neurons. beta-NGF signals through the low affinity nerve growth factor receptor (LNGFR) and the tropomyosin receptor kinase A (TrkA) to activate PI3K, Ras, and PLC signaling pathways. beta-NGF is also involved in the growth, differentiation, and survival of B lymphocytes. Human, mouse, and rat beta-NGF proteins are cross-reactive. |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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