PDF DatasheetMouse IL33 / Interleukin-33 / NF-HEV Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant IL33 / Interleukin-33 / NF-HEV based upon sequence from: Mouse
Host: QP5444 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Bioactive
Application Notes: Please contact us for application specific information for QP5444.
Bioactivity Data: BioActivity: Shows bioactivity at a concentration of 2 ng/mL in the D10S cell proliferation assay. The bioactivity acceptance criteria is set at 5 x 10^5 units/mg.
Monomer or Dimer: Monomer
Amino Acid Sequence: MSIQGTSLLT QSPASLSTYN DQSVSFVLEN GCYVINVDDS GKDQEQDQVL LRYYESPCPA SQSGDGVDGK KLMVNMSPIK DTDIWLHAND KDYSVELQRG DVSPPEQAFF VLHKKSSDFV SFECKNLPGT YIGVKDNQLA LVEEKDESCN NIMFKLSKI
Purity: Greater than 90 as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Mouse IL33 / Interleukin-33 / NF-HEV Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: 10 mM sodium phosphate, pH 7.5
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.
| Recombinant Mouse IL33 / Interleukin-33 / NF-HEV Protein General Information | |
|---|---|
| Alternate Names | |
| IL33, Interleukin-33, NF-HEV Protein, NF-HEV, C9orf26, DVS27, IL1F11, NFEHEV | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | IL33 |
| Entrez Gene ID | 77125 |
| Ensemble Gene ID | ENSMUSG00000024810 |
| RefSeq Protein Accession(s) | NP_001158196.1 |
| RefSeq mRNA Accession(s) | NM_001164724.1, NM_133775.2, XM_006527463.3, XM_011247399.2 |
| UniProt ID(s) | Q8BVZ5 |
| UniGene ID(s) | Mm.182359 |
| COSMIC ID Link(s) | IL33 |
| KEGG Gene ID(s) | mmu:77125 |
| General Description of Recombinant Mouse IL33 / Interleukin-33 / NF-HEV Protein. | |
| Interleukin 33 (IL-33) is a member of the IL-1 cytokine family and is constitutively expressed in smooth muscle and airway epithelial cells. IL-33 signals through the interleukin 1 receptor-like 1 (IL-1R1) and interleukin-1 receptor accessory protein (IL1RAP) receptors to ativate NF-?B and MAPK signaling pathways. IL-33 functions to induce type 2 cytokine production in polarized Type 2 T helper (Th2) cells. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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