PDF DatasheetMouse MCP-3 / CCL7 Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant MCP-3 / CCL7 based upon sequence from: Mouse
Host: QP5450 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Bioactive
Application Notes: Please contact us for application specific information for QP5450.
Bioactivity Data: CCL7 / MCP-3 bioactivity was examined in a THP-1 cell migration assay. Significant chemotaxis of THP-1 cells was observable at concentrations of CCL7 greater than 1 ug/ml.
Monomer or Dimer: Monomer
Amino Acid Sequence: QPDGPNASTC CYVKKQKIPK RNLKSYRRIT SSRCPWEAVI FKTKKGMEVC AEAHQKWVEE AIAYLDMKTP TPKP
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Mouse MCP-3 / CCL7 Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: Sterile filtered (0.22 um) solution containing 0.1% TFA
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.
| Recombinant Mouse MCP-3 / CCL7 Protein General Information | |
|---|---|
| Alternate Names | |
| MCP-3, CCL7, MCP-3, SCYA7, FIC, SCYA6, MARC, MCP3, NC28 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CCL7 |
| Entrez Gene ID | 20306 |
| Ensemble Gene ID | ENSMUSG00000035373 |
| RefSeq Protein Accession(s) | NP_038682.1 |
| RefSeq mRNA Accession(s) | NM_013654.3 |
| UniProt ID(s) | Q03366 |
| UniGene ID(s) | Mm.341574 |
| COSMIC ID Link(s) | CCL7 |
| KEGG Gene ID(s) | mmu:20306 |
| General Description of Recombinant Mouse MCP-3 / CCL7 Protein . | |
| Monocyte chemotactic protein 3 (MCP-3), also called CCL7, is produced by macrophages and tumor cell lines. MCP-3 signals through the G protein-coupled receptors CCR1, CCR2, and CCR3. MCP-3 chemoattracts monocytes and regulates macrophage function during inflammation and metastasis. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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