PDF DatasheetHuman MCP-3 / CCL7 Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant MCP-3 / CCL7 based upon sequence from: Human
Host: QP10230 protein expressed in E. coli.
Tag: Untagged
Protein Construction: A DNA sequence encoding the Human MCP-3 / CCL7, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP10230.
Bioactivity Data: Equivalent or superior bioactivity to competitors. Data available upon request. The biologically active determined by a chemotaxis bioassay using human monocytes is in a concentration range of 10-100 ng/ml.
Full Length? Partial (see sequence information for more details).
Amino Acid Sequence: QPVGINTSTT CCYRFINKKI PKQRLESYRR TTSSHCPREA VIFKTKLDKE ICADPTQKWV QDFMKHLDKK TQTPKL
Purity: Greater than 97% as determined by SDS-PAGE and HPLC.
Reconstitution Instructions:
Concentration of Human MCP-3 / CCL7 Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than 1.0 EU/ug as determined by LAL method.
Buffer: 0.2 um filtered PBS, pH 7.4, lyophilized
Storage Conditions: Store at -20C to -80C.
| Recombinant Human MCP-3 / CCL7 Protein General Information | |
|---|---|
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CCL7 |
| Entrez Gene ID | 6354 |
| Ensemble Gene ID | ENSG00000108688 |
| RefSeq Protein Accession(s) | NP_006264.2 |
| RefSeq mRNA Accession(s) | NM_006273.3 |
| UniProt ID(s) | P80098 |
| UniGene ID(s) | Hs.251526 |
| HGNC ID(s) | HGNC:10634 |
| COSMIC ID Link(s) | CCL7 |
| KEGG Gene ID(s) | hsa:6354 |
| PharmGKB ID(s) | PA35566 |
| General Description of Recombinant Human MCP-3 / CCL7 Protein. | |
| Chemotactic factor that attracts monocytes and eosinophils, but not neutrophils. Augments monocyte anti-tumor activity. Also induces the release of gelatinase B. This protein can bind heparin. Binds to CCR1, CCR2 and CCR3. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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