PDF DatasheetHuman MIF / GLIF Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant MIF / GLIF based upon sequence from: Human
Host: QP10174 protein expressed in E. coli.
Tag: His
Protein Construction: A DNA sequence encoding the Human MIF / GLIF, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP10174.
Bioactivity Data: Equivalent or superior bioactivity to competitors. Data available upon request. The specific activity is determined by binding rhCD74 in a functional ELISA.
Full Length? Partial (see sequence information for more details).
Amino Acid Sequence: MPMFIVNTNV PRASVPDGFL SELTQQLAQA TGKPPQYIAV HVVPDQLMAF GGSSEPCALC SLHSIGKIGG AQNRSYSKLL CGLLAERLRI SPDRVYINYY DMNAANVGWN NSTFALEHHH HHH
Purity: Greater than 95% as determined by SDS-PAGE and HPLC.
Reconstitution Instructions:
Concentration of Human MIF / GLIF Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than 1.0 EU/ug as determined by LAL method.
Buffer: 0.2 um filtered PBS, pH 7.4, lyophilized
Storage Conditions: Store at -20C to -80C.
| Recombinant Human MIF / GLIF Protein General Information | |
|---|---|
| Alternate Names | |
| MIF; GLIF; MMIF; GLIF; GIF | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | MIF |
| Entrez Gene ID | 4282 |
| Ensemble Gene ID | ENSG00000240972 |
| RefSeq Protein Accession(s) | NP_002406.1 |
| RefSeq mRNA Accession(s) | NM_002415.1 |
| UniProt ID(s) | P14174 |
| UniGene ID(s) | Hs.407995 |
| HGNC ID(s) | HGNC:7097 |
| COSMIC ID Link(s) | MIF |
| KEGG Gene ID(s) | hsa:4282 |
| PharmGKB ID(s) | PA30819 |
| General Description of Recombinant Human MIF / GLIF Protein. | |
| Pro-inflammatory cytokine. Involved in the innate immune response to bacterial pathogens. The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense. Counteracts the anti-inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase and dopachrome tautomerase activity (in vitro), but the physiological substrate is not known. It is not clear whether the tautomerase activity has any physiological relevance, and whether it is important for cytokine activity. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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