PDF DatasheetHuman I-TAC / CXCL11 Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant I-TAC / CXCL11 based upon sequence from: Human
Host: QP10215 protein expressed in E. coli.
Tag: Untagged
Protein Construction: A DNA sequence encoding the Human I-TAC / CXCL11, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP10215.
Bioactivity Data: Equivalent or superior bioactivity to competitors. Data available upon request. The biological activity determined by a chemotaxis bioassay using human IL-2 activated human T-lymphocytes is in a concentration range of 0.1-10 ng/ml.
Full Length? Partial (see sequence information for more details).
Amino Acid Sequence: FPMFKRGRCL CIGPGVKAVK VADIEKASIM YPSNNCDKIE VIITLKENKG QRCLNPKSKQ ARLIIKKVER KNF
Purity: Greater than 97% as determined by SDS-PAGE and HPLC.
Reconstitution Instructions:
Concentration of Human I-TAC / CXCL11 Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than 1.0 EU/ug as determined by LAL method.
Buffer: 0.2 um filtered PBS, pH 7.4, lyophilized
Storage Conditions: Store at -20C to -80C.
| Recombinant Human I-TAC / CXCL11 Protein General Information | |
|---|---|
| Alternate Names | |
| I-TAC; CXCL11; I-TAC; IP-9; SCYB11; IP9; SCYB9B; H174; b-R1 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CXCL11 |
| Entrez Gene ID | 6373 |
| Ensemble Gene ID | ENSG00000169248 |
| RefSeq Protein Accession(s) | NP_001289052.1 |
| RefSeq mRNA Accession(s) | NM_001302123.1, NM_005409.4 |
| UniProt ID(s) | O14625 |
| UniGene ID(s) | Hs.632592 |
| HGNC ID(s) | HGNC:10638 |
| COSMIC ID Link(s) | CXCL11 |
| KEGG Gene ID(s) | hsa:6373 |
| PharmGKB ID(s) | PA35569 |
| General Description of Recombinant Human I-TAC / CXCL11 Protein. | |
| Chemotactic for interleukin-activated T-cells but not unstimulated T-cells, neutrophils or monocytes. Induces calcium release in activated T-cells. Binds to CXCR3. May play an important role in CNS diseases which involve T-cell recruitment. May play a role in skin immune responses. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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