PDF DatasheetHuman Fractalkine / CX3CL1 Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant Fractalkine / CX3CL1 based upon sequence from: Human
Host: QP10222 protein expressed in E. coli.
Tag: Untagged
Protein Construction: A DNA sequence encoding the Human Fractalkine / CX3CL1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP10222.
Bioactivity Data: Equivalent or superior bioactivity to competitors. Data available upon request. The biological activity determined by a chemotaxis bioassay using human T-lymphocytes is in a concentration of 5.0-10 ng/ml.
Full Length? Partial (see sequence information for more details).
Amino Acid Sequence: QHHGVTKCNI TCSKMTSKIP VALLIHYQQN QASCGKRAII LETRQHRLFC ADPKEQWVKD AMQHLDRQAA ALTRNG
Purity: Greater than 97% as determined by SDS-PAGE and HPLC.
Reconstitution Instructions:
Concentration of Human Fractalkine / CX3CL1 Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than 1.0 EU/ug as determined by LAL method.
Buffer: 0.2 um filtered PBS, pH 7.4, lyophilized
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Fractalkine / CX3CL1 Protein General Information | |
|---|---|
| Alternate Names | |
| Fractalkine; CX3CL1; ABCD-3; C3Xkine; NTT; SCYD1; CXC3; NTN; fractalkine; CXC3C; neurotactin | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CX3CL1 |
| Entrez Gene ID | 6376 |
| Ensemble Gene ID | ENSG00000006210 |
| RefSeq Protein Accession(s) | NP_001291321.1 |
| RefSeq mRNA Accession(s) | NM_001304392.1, NM_002996.4 |
| UniProt ID(s) | P78423 |
| UniGene ID(s) | Hs.531668 |
| HGNC ID(s) | HGNC:10647 |
| COSMIC ID Link(s) | CX3CL1 |
| KEGG Gene ID(s) | hsa:6376 |
| PharmGKB ID(s) | PA35577 |
| General Description of Recombinant Human Fractalkine / CX3CL1 Protein. | |
| The soluble form is chemotactic for T-cells and monocytes, but not for neutrophils. The membrane-bound form promotes adhesion of those leukocytes to endothelial cells. May play a role in regulating leukocyte adhesion and migration processes at the endothelium. Binds to CX3CR1. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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