Rat Fractalkine / CX3CL1 Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant Fractalkine / CX3CL1 based upon sequence from: Rat
Host: QP10291 protein expressed in E. coli.
Tag: Untagged
Protein Construction: A DNA sequence encoding the Rat Fractalkine / CX3CL1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP10291.
Bioactivity Data: Equivalent or superior bioactivity to competitors. Data available upon request. The biological activity determined by a chemotaxis bioassay using human monocytes is in a concentration of 5.0-10 ng/ml.
Full Length? Partial (see sequence information for more details).
Amino Acid Sequence: QHLGMTKCNI TCHKMTSPIP VTLLIHYQLN QESCGKRAII LETRQHRHFC ADPKEKWVQD AMKHLDHQTA ALTRNG
Purity: Greater than 95% as determined by SDS-PAGE and HPLC.
Reconstitution Instructions:
Concentration of Rat Fractalkine / CX3CL1 Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than 1.0 EU/ug as determined by LAL method.
Buffer: 0.2 um filtered PBS, pH 7.4, lyophilized
Storage Conditions: Store at -20C to -80C.
Recombinant Rat Fractalkine / CX3CL1 Protein General Information | |
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Curated Database and Bioinformatic Data | |
Gene Symbol | CX3CL1 |
Entrez Gene ID | 89808 |
RefSeq Protein Accession(s) | NP_604450.1 |
RefSeq mRNA Accession(s) | NM_134455.1 |
UniProt ID(s) | O55145 |
COSMIC ID Link(s) | CX3CL1 |
KEGG Gene ID(s) | rno:89808 |
General Description of Recombinant Rat Fractalkine / CX3CL1 Protein. | |
The soluble form is chemotactic for T-cells and monocytes, but not for neutrophils. The membrane-bound form promotes adhesion of those leukocytes to endothelial cells. May play a role in regulating leukocyte adhesion and migration processes at the endothelium. Binds to CX3CR1. |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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