PDF DatasheetHuman CCL8 / MCP-2 Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant CCL8 / MCP-2 based upon sequence from: Human
Host: QP10231 protein expressed in E. coli.
Tag: Untagged
Protein Construction: A DNA sequence encoding the Human CCL8 / MCP-2, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP10231.
Bioactivity Data: Equivalent or superior bioactivity to competitors. Data available upon request. The biological activity determined by a chemotaxis bioassay using human peripheral blood monocytes is in a concentration range of 10-100 ng/ml.
Full Length? Partial (see sequence information for more details).
Amino Acid Sequence: QPDSVSIPIT CCFNVINRKI PIQRLESYTR ITNIQCPKEA VIFKTKRGKE VCADPKERWV RDSMKHLDQI FQNLKP
Purity: Greater than 96% as determined by SDS-PAGE and HPLC.
Reconstitution Instructions:
Concentration of Human CCL8 / MCP-2 Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than 1.0 EU/ug as determined by LAL method.
Buffer: 0.2 um filtered PBS, pH 7.4, lyophilized
Storage Conditions: Store at -20C to -80C.
| Recombinant Human CCL8 / MCP-2 Protein General Information | |
|---|---|
| Alternate Names | |
| CCL8; MCP-2; AB023418; Scya8; Mcp2; HC14; MCP-2; 1810063B20Rik | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CCL8 |
| Entrez Gene ID | 6355 |
| Ensemble Gene ID | ENSG00000108700 |
| RefSeq Protein Accession(s) | NP_005614.2 |
| RefSeq mRNA Accession(s) | NM_005623.2 |
| UniProt ID(s) | P80075 |
| UniGene ID(s) | Hs.271387 |
| HGNC ID(s) | HGNC:10635 |
| COSMIC ID Link(s) | CCL8 |
| KEGG Gene ID(s) | hsa:6355 |
| PharmGKB ID(s) | PA35567 |
| General Description of Recombinant Human CCL8 / MCP-2 Protein. | |
| Chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils. May play a role in neoplasia and inflammatory host responses. This protein can bind heparin. The processed form MCP-2(6-76) does not show monocyte chemotactic activity, but inhibits the chemotactic effect most predominantly of CCL7, and also of CCL2 and CCL5 and CCL8. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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