PDF DatasheetMouse C-C motif chemokine 25 Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant C-C motif chemokine 25 based upon sequence from: Mouse
Host: QP10278 protein expressed in E. coli.
Tag: Untagged
Protein Construction: A DNA sequence encoding the Mouse C-C motif chemokine 25, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP10278.
Bioactivity Data: Equivalent or superior bioactivity to competitors. Data available upon request. The biological activity determined by a chemotaxis bioassay using human monocytes is in a concentration range of 5.0-50 ng/ml.
Full Length? Partial (see sequence information for more details).
Amino Acid Sequence: QGAFEDCCLG YQHRIKWNVL RHARNYHQQE VSGSCNLRAV RFYFRQKVVC GNPEDMNVKR AIRILTARKR LVHWKSASDS QTERKKSNHM KSKVENPNST SVRSATLGHP RMVMMPRKTN N
Purity: Greater than 95% as determined by SDS-PAGE and HPLC.
Reconstitution Instructions:
Concentration of Mouse C-C motif chemokine 25 Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than 1.0 EU/ug as determined by LAL method.
Buffer: 0.2 um filtered PBS, pH 7.4, lyophilized
Storage Conditions: Store at -20C to -80C.
| Recombinant Mouse C-C motif chemokine 25 Protein General Information | |
|---|---|
| Alternate Names | |
| Scya25; TECK; CKb15; A130072A22Rik; AI852536 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CCL25 |
| Entrez Gene ID | 20300 |
| Ensemble Gene ID | ENSMUSG00000023235 |
| RefSeq Protein Accession(s) | NP_033164.1 |
| RefSeq mRNA Accession(s) | NM_009138.3, XM_011242043.2, XM_011242044.2 |
| UniProt ID(s) | O35903 |
| UniGene ID(s) | Mm.7275 |
| COSMIC ID Link(s) | Ccl25 |
| KEGG Gene ID(s) | mmu:20300 |
| General Description of Recombinant Mouse C-C motif chemokine 25 Protein. | |
| Potentially involved in T-cell development. Recombinant protein shows chemotactic activity on thymocytes, macrophages, THP-1 cells, and dendritics cells but is inactive on peripheral blood lymphocytes and neutrophils. Binds to CCR9. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
There are no reviews yet.