PDF DatasheetHuman C-C motif chemokine 25 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant C-C motif chemokine 25 based upon sequence from Human
Host: QP5774 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) C-C motif chemokine 25, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP5774.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Gln24 – Leu150
Amino Acid Sequence: QGVFEDCCLA YHYPIGWAVL RRAWTYRIQE VSGSCNLPAA IFYLPKRHRK VCGNPKSREV QRAMKLLDAR NKVFAKLHHN TQTFQAGPHA VKKLSSGNSK LSSSKFSNPI SSSKRNVSLL ISANSGL
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human C-C motif chemokine 25 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human C-C motif chemokine 25 Protein General Information | |
|---|---|
| Alternate Names | |
| SCYA25, TECK, Ckb15 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CCL25 |
| Entrez Gene ID | 6370 |
| Ensemble Gene ID | ENSG00000131142 |
| RefSeq Protein Accession(s) | NP_001188288.1 |
| RefSeq mRNA Accession(s) | NM_001201359.1, NM_005624.3, XM_011528177.2, XM_017027120.1, XM_017027121.1, XM_017027122.1 |
| UniProt ID(s) | O15444 |
| UniGene ID(s) | Hs.310511 |
| HGNC ID(s) | HGNC:10624 |
| COSMIC ID Link(s) | CCL25 |
| KEGG Gene ID(s) | hsa:6370 |
| PharmGKB ID(s) | PA35556 |
| General Description of Recombinant Human C-C motif chemokine 25 Protein. | |
| Potentially involved in T-cell development. Recombinant protein shows chotactic activity on thymocytes, macrophages, THP-1 cells, and dendritics cells but is inactive on peripheral blood lymphocytes and neutrophils. Binds to CCR9. Isoform 2 is an antagonist of isoform 1. Binds to atypical chokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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