PDF DatasheetHuman IL17F / IL-17F Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant IL17F / IL-17F based upon sequence from: Human
Host: QP10322 protein expressed in E. coli.
Tag: Untagged
Protein Construction: A DNA sequence encoding the Human IL17F / IL-17F, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP10322.
Bioactivity Data: Equivalent or superior bioactivity to competitors. Data available upon request. The ED50 as determined by inducing IL-6 secretion of murine NIH/3T3 cells is less than 20 ng/ml, corresponding to a specific activity of > 5.0 × 104 IU/mg.
Full Length? Partial (see sequence information for more details).
Amino Acid Sequence: MRKIPKVGHT FFQKPESCPP VPGGSMKLDI GIINENQRVS MSRNIESRST SPWNYTVTWD PNRYPSEVVQ AQCRNLGCIN AQGKEDISMN SVPIQQETLV VRRKHQGCSV SFQLEKVLVT VGCTCVTPVI HHVQ
Purity: Greater than 95% as determined by SDS-PAGE and HPLC.
Reconstitution Instructions:
Concentration of Human IL17F / IL-17F Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than 1.0 EU/ug as determined by LAL method.
Buffer: 0.2 um filtered PBS, pH 7.4, lyophilized
Storage Conditions: Store at -20C to -80C.
| Recombinant Human IL17F / IL-17F Protein General Information | |
|---|---|
| Alternate Names | |
| IL17F; IL-17F; IL-17F; ML-1; ML1; CANDF6 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | IL17F |
| Entrez Gene ID | 112744 |
| Ensemble Gene ID | ENSG00000112116 |
| RefSeq Protein Accession(s) | NP_443104.1 |
| RefSeq mRNA Accession(s) | NM_052872.3, XM_011514276.1 |
| UniProt ID(s) | Q96PD4 |
| UniGene ID(s) | Hs.272295 |
| HGNC ID(s) | HGNC:16404 |
| COSMIC ID Link(s) | IL17F |
| KEGG Gene ID(s) | hsa:112744 |
| PharmGKB ID(s) | PA29800 |
| General Description of Recombinant Human IL17F / IL-17F Protein. | |
| Stimulates the production of other cytokines such as IL-6, IL-8 and granulocyte colony-stimulating factor, and can regulate cartilage matrix turnover. Stimulates PBMC and T-cell proliferation. Inhibits angiogenesis. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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