PDF DatasheetHuman FLT3L / Flt3 ligand Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant FLT3L / Flt3 ligand based upon sequence from: Human
Host: QP10358 protein expressed in E. coli.
Tag: Untagged
Protein Construction: A DNA sequence encoding the Human FLT3L / Flt3 ligand, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP10358.
Bioactivity Data: Equivalent or superior bioactivity to competitors. Data available upon request. The ED50 as determined by a cell proliferation assay using human AML5 cells is less than 1.0 ng/ml, corresponding to a specific activity of > 1.0 × 106 IU/mg.
Full Length? Partial (see sequence information for more details).
Amino Acid Sequence: TQDCSFQHSP ISSDFAVKIR ELSDYLLQDY PVTVASNLQD EELCGGLWRL VLAQRWMERL KTVAGSKMQG LLERVNTEIH FVTKCAFQPP PSCLRFVQTN ISRLLQETSE QLVALKPWIT RQNFSRCLEL QCQPDSSTLP PPWSPRPLEA TAPTA
Purity: Greater than 97% as determined by SDS-PAGE and HPLC.
Reconstitution Instructions:
Concentration of Human FLT3L / Flt3 ligand Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than 1.0 EU/ug as determined by LAL method.
Buffer: 0.2 um filtered PBS, pH 7.0, lyophilized
Storage Conditions: Store at -20C to -80C.
| Recombinant Human FLT3L / Flt3 ligand Protein General Information | |
|---|---|
| Alternate Names | |
| FLT3L; Flt3 ligand; Flt3lg; Ly72L | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | FLT3LG |
| Entrez Gene ID | 2323 |
| Ensemble Gene ID | ENSG00000090554 |
| RefSeq Protein Accession(s) | NP_001191431.1 |
| RefSeq mRNA Accession(s) | NM_001204502.1, NM_001204503.1, NM_001278637.1, NM_001278638.1, NM_001459.3, XM_011526682.2 |
| UniProt ID(s) | P49771 |
| UniGene ID(s) | Hs.428 |
| HGNC ID(s) | HGNC:3766 |
| COSMIC ID Link(s) | FLT3LG |
| KEGG Gene ID(s) | hsa:2323 |
| PharmGKB ID(s) | PA28182 |
| General Description of Recombinant Human FLT3L / Flt3 ligand Protein. | |
| Stimulates the proliferation of early hematopoietic cells by activating FLT3. Synergizes well with a number of other colony stimulating factors and interleukins. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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