PDF DatasheetHuman CNTF Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant CNTF based upon sequence from: Human
Host: QP10413 protein expressed in E. coli.
Tag: Untagged
Protein Construction: A DNA sequence encoding the Human CNTF, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP10413.
Bioactivity Data: Equivalent or superior bioactivity to competitors. Data available upon request. The ED50 as determined by a cell proliferation assay using human TF-1 cells is less than 150 ng/ml, corresponding to a specific activity of > 6.7 × 103 IU/mg.
Full Length? Partial (see sequence information for more details).
Amino Acid Sequence: MAFTEHSPLT PHRRDLCSRS IWLARKIRSD LTALTESYVK HQGLNKNINL DSADGMPVAS TDQWSELTEA ERLQENLQAY RTFHVLLARL LEDQQVHFTP TEGDFHQAIH TLLLQVAAFA YQIEELMILL EYKIPRNEAD GMPINVGDGG LFEKKLWGLK VLQELSQWTV RSIHDLRFIS SHQTGIPARG SHYIANNKKM
Purity: Greater than 97% as determined by SDS-PAGE and HPLC.
Reconstitution Instructions:
Concentration of Human CNTF Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than 1.0 EU/ug as determined by LAL method.
Buffer: 0.2 um filtered PBS, pH 7.4, lyophilized
Storage Conditions: Store at -20C to -80C.
| Recombinant Human CNTF Protein General Information | |
|---|---|
| Alternate Names | |
| CNTF; AI429687 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CNTF |
| Entrez Gene ID | 1270 |
| Ensemble Gene ID | ENSG00000242689 |
| RefSeq Protein Accession(s) | NP_000605.1 |
| RefSeq mRNA Accession(s) | NM_000614.3 |
| UniProt ID(s) | P26441 |
| UniGene ID(s) | Hs.524920 |
| HGNC ID(s) | HGNC:2169 |
| COSMIC ID Link(s) | CNTF |
| KEGG Gene ID(s) | hsa:1270 |
| PharmGKB ID(s) | PA26683 |
| General Description of Recombinant Human CNTF Protein. | |
| CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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