PDF DatasheetHuman BTC / Betacellulin Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant BTC / Betacellulin based upon sequence from: Human
Host: QP10416 protein expressed in E. coli.
Tag: Untagged
Protein Construction: A DNA sequence encoding the Human BTC / Betacellulin, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP10416.
Bioactivity Data: Equivalent or superior bioactivity to competitors. Data available upon request. The ED50 as determined by a cell proliferation assay using murine Balb/c 3T3 cells is less than 0.05 ng/ml, corresponding to a specific activity of > 2.0 × 107 IU/mg.
Full Length? Partial (see sequence information for more details).
Amino Acid Sequence: DGNSTRSPET NGLLCGDPEE NCAATTTQSK RKGHFSRCPK QYKHYCIKGR CRFVVAEQTP SCVCDEGYIG ARCERVDLFY
Purity: Greater than 98% as determined by SDS-PAGE and HPLC.
Reconstitution Instructions:
Concentration of Human BTC / Betacellulin Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than 1.0 EU/ug as determined by LAL method.
Buffer: 0.2 um filtered PBS, pH 7.4, with 0.02 % Tween-20, lyophilized
Storage Conditions: Store at -20C to -80C.
| Recombinant Human BTC / Betacellulin Protein General Information | |
|---|---|
| Alternate Names | |
| BTC; Betacellulin; EGK_15786 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | BTC |
| Entrez Gene ID | 685 |
| Ensemble Gene ID | ENSG00000174808 |
| RefSeq Protein Accession(s) | NP_001303892.1 |
| RefSeq mRNA Accession(s) | NM_001316963.1, NM_001729.3, XM_011532211.1 |
| UniProt ID(s) | P35070 |
| UniGene ID(s) | Hs.591704 |
| HGNC ID(s) | HGNC:1121 |
| COSMIC ID Link(s) | BTC |
| KEGG Gene ID(s) | hsa:685 |
| PharmGKB ID(s) | PA25442 |
| General Description of Recombinant Human BTC / Betacellulin Protein. | |
| Growth factor that binds to EGFR, ERBB4 and other EGF receptor family members. Potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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