PDF DatasheetHuman Beta Defensin 103AB Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant Beta Defensin 103AB based upon sequence from: Human
Host: QP10431 protein expressed in E. coli.
Tag: Untagged
Protein Construction: A DNA sequence encoding the Human Beta Defensin 103AB, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP10431.
Bioactivity Data: Equivalent or superior bioactivity to competitors. Data available upon request. The ED50 as determined by anti-microbial activity against E.coli. is less than 30 ug/ml, corresponding to a specific activity of > 33.3 IU/mg.
Full Length? Partial (see sequence information for more details).
Amino Acid Sequence: GIINTLQKYY CRVRGGRCAV LSCLPKEEQI GKCSTRGRKC CRRKK
Purity: Greater than 98% as determined by SDS-PAGE and HPLC.
Reconstitution Instructions:
Concentration of Human Beta Defensin 103AB Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than 1.0 EU/ug as determined by LAL method.
Buffer: 0.2 um filtered 20 mM PBS, pH 7.4, 130 mM NaCl, lyophilized
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Beta Defensin 103AB Protein General Information | |
|---|---|
| Alternate Names | |
| DEFB103A; DEFB103B, Beta Defensin a/b | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | DEFB103AB |
| Entrez Gene ID | 414325 |
| Ensemble Gene ID | ENSG00000176797 |
| RefSeq Protein Accession(s) | NP_001075020.1 |
| RefSeq mRNA Accession(s) | NM_001081551.3, NM_018661.4, XM_017030192.1 |
| UniProt ID(s) | P81534 |
| UniGene ID(s) | Hs.283082 |
| HGNC ID(s) | HGNC:15967 |
| KEGG Gene ID(s) | hsa:414325 |
| PharmGKB ID(s) | PA134933952 |
| General Description of Recombinant Human Beta Defensin 103AB Protein. | |
| Exhibits antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Kills multiresistant S.aureus and vancomycin-resistant E.faecium. No significant hemolytic activity was observed. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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