PDF DatasheetHuman Galectin-3 / LGALS3 Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant Galectin-3 / LGALS3 based upon sequence from Human
Host: QP1087 protein expressed in E. coli.
Tag: Untagged
Protein Construction: A DNA sequence encoding the Human Galectin-3 / LGALS3, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP1087.
Bioactivity Data: Equivalent or superior bioactivity to competitors. Data available upon request. The ED50 as determined by its ability to agglutinate human red blood cells is less than 10 ug/ml.
Full Length? Partial (see sequence information for more details).
Amino Acid Sequence: ADNFSLHDAL SGSGNPNPQG WPGAWGNQPA GAGGYPGASY PGAYPGQAPP GAYPGQAPPG AYPGAPGAYP GAPAPGVYPG PPSGPGAYPS SGQPSATGAY PATGPYGAPA GPLIVPYNLP LPGGVVPRML ITILGTVKPN ANRIALDFQR GNDVAFHFNP RFNENNRRVI VCNTKLDNNW GREERQSVFP FESGKPFKIQ VLVEPDHFKV AVNDAHLLQY NHRVKKLNEI SKLGISGDID LTSASYTMI
Purity: Greater than 98% as determined by SDS-PAGE and HPLC.
Reconstitution Instructions: A Certificate of Analysis (CofA) will be sent along with the protein and will contain the proper reconstitution instructions.
Concentration of Human Galectin-3 / LGALS3 Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than 1.0 EU/ug as determined by LAL method.
Buffer: 0.2 um filtered 20 mM PBS, pH 7.4, 150mM NaCl, lyophilized
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Galectin-3 / LGALS3 Protein General Information | |
|---|---|
| Alternate Names | |
| Galectin-3, LGALS3 Protein, Low Endotoxin, GAL3, LGALS2, GALIG, L31, GALBP, CBP35, MAC2 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | LGALS3 |
| Entrez Gene ID | 3958 |
| Ensemble Gene ID | ENSG00000131981 |
| RefSeq Protein Accession(s) | NP_002297.2 |
| RefSeq mRNA Accession(s) | NM_002306.3 |
| UniProt ID(s) | P17931 |
| UniGene ID(s) | Hs.531081 |
| HGNC ID(s) | HGNC:6563 |
| COSMIC ID Link(s) | LGALS3 |
| KEGG Gene ID(s) | hsa:3958 |
| PharmGKB ID(s) | PA30340 |
| General Description of Recombinant Human Galectin-3 / LGALS3 Protein. | |
| Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity). In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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