PDF DatasheetHuman BCL10 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant BCL10 based upon sequence from Human
Host: QP5709 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) BCL10, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP5709.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Gln233
Amino Acid Sequence: MEPTAPSLTE EDLTEVKKDA LENLRVYLCE KIIAERHFDH LRAKKILSRE DTEEISCRTS SRKRAGKLLD YLQENPKGLD TLVESIRREK TQNFLIQKIT DEVLKLRNIK LEHLKGLKCS SCEPFPDGAT NNLSRSNSDE SNFSEKLRAS TVMYHPEGES STTPFFSTNS SLNLPVLEVG RTENTIFSST TLPRPGDPGA PPLPPDLQLE EEGTCANSSE MFLPLRSRTV SRQ
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human BCL10 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human BCL10 Protein General Information | |
|---|---|
| Alternate Names | |
| BCL10, CIPER, mE10, IMD37, CLAP, CARMEN, c-E10 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | BCL10 |
| Entrez Gene ID | 8915 |
| Ensemble Gene ID | ENSG00000142867 |
| RefSeq Protein Accession(s) | NP_003912.1 |
| RefSeq mRNA Accession(s) | NM_003921.4 |
| UniProt ID(s) | O95999 |
| UniGene ID(s) | Hs.193516 |
| HGNC ID(s) | HGNC:989 |
| COSMIC ID Link(s) | BCL10 |
| KEGG Gene ID(s) | hsa:8915 |
| PharmGKB ID(s) | PA25299 |
| General Description of Recombinant Human BCL10 Protein. | |
| Involved in adaptive immune response . Promotes apoptosis, pro-caspase-9 maturation and activation of NF-kappa-B via NIK and IKK. May be an adapter protein between upstream TNFR1-TRADD-RIP complex and the downstream NIK-IKK-IKAP complex. Is a substrate for MALT1 . | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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