PDF DatasheetHuman BDNF Protein Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant BDNF Protein based upon sequence from Human
Host: QP5714 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) BDNF Protein, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP5714.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: His129 – Arg247
Amino Acid Sequence: HSDPARRGEL SVCDSISEWV TAADKKTAVD MSGGTVTVLE KVPVSKGQLK QYFYETKCNP MGYTKEGCRG IDKRHWNSQC RTTQSYVRAL TMDSKKRIGW RFIRIDTSCV CTLTIKRGR
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human BDNF Protein Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human BDNF Protein Protein (129-247aa) General Information | |
|---|---|
| Alternate Names | |
| BDNF, BDNF protein, Brain-derived neurotrophic factor | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | BDNF |
| Entrez Gene ID | 627 |
| Ensemble Gene ID | ENSG00000176697 |
| RefSeq Protein Accession(s) | NP_001137277.1 |
| RefSeq mRNA Accession(s) | NM_001143805.1, NM_001143806.1, NM_001143807.1, NM_001143808.1, NM_001143809.1, NM_001143810.1, NM_001143811.1, NM_001143812.1, NM_001143813.1, NM_001143814.1, NM_001143816.1, NM_001709.4, NM_170731.4, NM_170732.4, NM_170733.3, NM_170734.3, NM_170735.5, XM_011520280.2 |
| UniProt ID(s) | P23560 |
| UniGene ID(s) | Hs.502182 |
| HGNC ID(s) | HGNC:1033 |
| COSMIC ID Link(s) | BDNF |
| KEGG Gene ID(s) | hsa:627 |
| PharmGKB ID(s) | PA31891 |
| General Description of Recombinant Human BDNF Protein Protein (129-247aa). | |
| During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systs. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is phasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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