PDF DatasheetHuman BDNF Protein Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant BDNF Protein based upon sequence from: Human
Host: QP8513 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) BDNF Protein, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8513.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Glu137 – Cys237
Amino Acid Sequence: ELSVCDSISE WVTAADKKTA VDMSGGTVTV LEKVPVSKGQ LKQYFYETKC NPMGYTKEGC RGIDKRHWNS QCRTTQSYVR ALTMDSKKRI GWRFIRIDTS C
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human BDNF Protein Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human BDNF Protein Protein (137-237aa) General Information | |
|---|---|
| Alternate Names | |
| BDNF; BDNF protein, Brain-derived neurotrophic factor | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | BDNF |
| Entrez Gene ID | 627 |
| Ensemble Gene ID | ENSG00000176697 |
| RefSeq Protein Accession(s) | NP_001137277.1 |
| RefSeq mRNA Accession(s) | NM_001143805.1, NM_001143806.1, NM_001143807.1, NM_001143808.1, NM_001143809.1, NM_001143810.1, NM_001143811.1, NM_001143812.1, NM_001143813.1, NM_001143814.1, NM_001143816.1, NM_001709.4, NM_170731.4, NM_170732.4, NM_170733.3, NM_170734.3, NM_170735.5, XM_011520280.2 |
| UniProt ID(s) | P23560 |
| UniGene ID(s) | Hs.502182 |
| HGNC ID(s) | HGNC:1033 |
| COSMIC ID Link(s) | BDNF |
| KEGG Gene ID(s) | hsa:627 |
| PharmGKB ID(s) | PA31891 |
| General Description of Recombinant Human BDNF Protein Protein (137-237aa). | |
| During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systs. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is phasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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