PDF DatasheetHuman Cystathionine beta-synthase Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Cystathionine beta-synthase based upon sequence from Human
Host: QP5767 protein expressed in E. coli.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Cystathionine beta-synthase, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP5767.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Pro2 – Lys551
Amino Acid Sequence: PSETPQAEVG PTGCPHRSGP HSAKGSLEKG SPEDKEAKEP LWIRPDAPSR CTWQLGRPAS ESPHHHTAPA KSPKILPDIL KKIGDTPMVR INKIGKKFGL KCELLAKCEF FNAGGSVKDR ISLRMIEDAE RDGTLKPGDT IIEPTSGNTG IGLALAAAVR GYRCIIVMPE KMSSEKVDVL RALGAEIVRT PTNARFDSPE SHVGVAWRLK NEIPNSHILD QYRNASNPLA HYDTTADEIL QQCDGKLDML VASVGTGGTI TGIARKLKEK CPGCRIIGVD PEGSILAEPE ELNQTEQTTY EVEGIGYDFI PTVLDRTVVD KWFKSNDEEA FTFARMLIAQ EGLLCGGSAG STVAVAVKAA QELQEGQRCV VILPDSVRNY MTKFLSDRWM LQKGFLKEED LTEKKPWWWH LRVQELGLSA PLTVLPTITC GHTIEILREK GFDQAPVVDE AGVILGMVTL GNMLSSLLAG KVQPSDQVGK VIYKQFKQIR LTDTLGRLSH ILEMDHFALV VHEQIQYHST GKSSQRQMVF GVVTAIDLLN FVAAQERDQK
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Cystathionine beta-synthase Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Cystathionine beta-synthase Protein General Information | |
|---|---|
| Alternate Names | |
| HIP4 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CBS |
| Entrez Gene ID | 102724560 |
| Ensemble Gene ID | ENSG00000160200 |
| RefSeq Protein Accession(s) | NP_000062.1 |
| RefSeq mRNA Accession(s) | NM_000071.2, NM_001178008.2, NM_001178009.2, NM_001320298.1, NM_001321073.1, XM_011529777.1, XM_011529781.1, XM_011529782.1, XM_011546094.1, XM_011546095.2, XM_011546097.2, XM_011546098.1, XM_011546099.1, XM_017028211.1, XM_017028212.1, XM_017028213.1, XM_017028214.1, XM_017028215.1, XM_017028216.1, XM_017028217.1, XM_017028218.1, XM_017028489.1, XM_017028490.1, XM_017028491.1, XM_017028492.1 |
| UniProt ID(s) | P35520 |
| UniGene ID(s) | Hs.533013 |
| HGNC ID(s) | HGNC:1550 |
| COSMIC ID Link(s) | CBS |
| KEGG Gene ID(s) | hsa:102724560 |
| PharmGKB ID(s) | PA26123 |
| General Description of Recombinant Human Cystathionine beta-synthase Protein. | |
| Only known pyridoxal phosphate-dependent enzyme that contains he. Important regulator of hydrogen sulfide, especially in the brain, utilizing cysteine instead of serine to catalyze the formation of hydrogen sulfide. Hydrogen sulfide is a gastratransmitter with signaling and cytoprotective effects such as acting as a neuromodulator in the brain to protect neurons against hypoxic injury . | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
There are no reviews yet.