PDF DatasheetHuman Cystathionine beta-synthase Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Cystathionine beta-synthase based upon sequence from Human
Host: QP5768 protein expressed in E.coli, Yeast..
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Cystathionine beta-synthase, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP5768.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Met1 – Arg413
Amino Acid Sequence: MPSETPQAEV GPTGCPHRSG PHSAKGSLEK GSPEDKEAKE PLWIRPDAPS RCTWQLGRPA SESPHHHTAP AKSPKILPDI LKKIGDTPMV RINKIGKKFG LKCELLAKCE FFNAGGSVKD RISLRMIEDA ERDGTLKPGD TIIEPTSGNT GIGLALAAAV RGYRCIIVMP EKMSSEKVDV LRALGAEIVR TPTNARFDSP ESHVGVAWRL KNEIPNSHIL DQYRNASNPL AHYDTTADEI LQQCDGKLDM LVASVGTGGT ITGIARKLKE KCPGCRIIGV DPEGSILAEP EELNQTEQTT YEVEGIGYDF IPTVLDRTVV DKWFKSNDEE AFTFARMLIA QEGLLCGGSA GSTVAVAVKA AQELQEGQRC VVILPDSVRN YMTKFLSDRW MLQKGFLKEE DLTEKKPWWW HLR
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Cystathionine beta-synthase Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Cystathionine beta-synthase Protein General Information | |
|---|---|
| Alternate Names | |
| HIP4 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CBS |
| Entrez Gene ID | 102724560 |
| Ensemble Gene ID | ENSG00000160200 |
| RefSeq Protein Accession(s) | NP_000062.1 |
| RefSeq mRNA Accession(s) | NM_000071.2, NM_001178008.2, NM_001178009.2, NM_001320298.1, NM_001321073.1, XM_011529777.1, XM_011529781.1, XM_011529782.1, XM_011546094.1, XM_011546095.2, XM_011546097.2, XM_011546098.1, XM_011546099.1, XM_017028211.1, XM_017028212.1, XM_017028213.1, XM_017028214.1, XM_017028215.1, XM_017028216.1, XM_017028217.1, XM_017028218.1, XM_017028489.1, XM_017028490.1, XM_017028491.1, XM_017028492.1 |
| UniProt ID(s) | P35520 |
| UniGene ID(s) | Hs.533013 |
| HGNC ID(s) | HGNC:1550 |
| COSMIC ID Link(s) | CBS |
| KEGG Gene ID(s) | hsa:102724560 |
| PharmGKB ID(s) | PA26123 |
| General Description of Recombinant Human Cystathionine beta-synthase Protein. | |
| Only known pyridoxal phosphate-dependent enzyme that contains he. Important regulator of hydrogen sulfide, especially in the brain, utilizing cysteine instead of serine to catalyze the formation of hydrogen sulfide. Hydrogen sulfide is a gastratransmitter with signaling and cytoprotective effects such as acting as a neuromodulator in the brain to protect neurons against hypoxic injury . | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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