PDF DatasheetHuman Cytochrome C Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Cytochrome C based upon sequence from Human
Host: QP5900 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Cytochrome C, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP5900.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Gly2 – Glu105
Amino Acid Sequence: GDVEKGKKIF IMKCSQCHTV EKGGKHKTGP NLHGLFGRKT GQAPGYSYTA ANKNKGIIWG EDTLMEYLEN PKKYIPGTKM IFVGIKKKEE RADLIAYLKK ATNE
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Cytochrome C Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Cytochrome C Protein General Information | |
|---|---|
| Alternate Names | |
| Cytochrome C, THC4, CYC, HCS | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CYCS |
| Entrez Gene ID | 54205 |
| Ensemble Gene ID | ENSG00000172115 |
| RefSeq Protein Accession(s) | NP_061820.1 |
| RefSeq mRNA Accession(s) | NM_018947.5 |
| UniProt ID(s) | P99999 |
| UniGene ID(s) | Hs.437060 |
| HGNC ID(s) | HGNC:19986 |
| COSMIC ID Link(s) | CYCS |
| KEGG Gene ID(s) | hsa:54205 |
| PharmGKB ID(s) | PA134981636 |
| General Description of Recombinant Human Cytochrome C Protein. | |
| Electron carrier protein. The oxidized form of the cytochrome c he group can accept an electron from the he group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.Plays a role in apoptosis. Suppression of the anti-apoptotic mbers or activation of the pro-apoptotic mbers of the Bcl-2 family leads to altered mitochondrial mbrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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