PDF DatasheetRat Steroid 17-alpha-hydroxylase / 17,20 lyase Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Steroid 17-alpha-hydroxylase / 17,20 lyase based upon sequence from Rat
Host: QP5906 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Rattus norvegicus (Rat) Steroid 17-alpha-hydroxylase/17,20 lyase, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP5906.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Thr507
Amino Acid Sequence: MWELVGLLLL ILAYFFWVKS KTPGAKLPRS LPSLPLVGSL PFLPRRGHMH VNFFKLQEKY GPIYSLRLGT TTTVIIGHYQ LAREVLIKKG KEFSGRPQMV TQSLLSDQGK GVAFADAGSS WHLHRKLVFS TFSLFKDGQK LEKLICQEAK SLCDMMLAHD KESIDLSTPI FMSVTNIICA ICFNISYEKN DPKLTAIKTF TEGIVDATGD RNLVDIFPWL TIFPNKGLEV IKGYAKVRNE VLTGIFEKCR EKFDSQSISS LTDILIQAKM NSDNNNSCEG RDPDVFSDRH ILATVGDIFG AGIETTTTVL KWILAFLVHN PEVKKKIQKE IDQYVGFSRT PTFNDRSHLL MLEATIREVL RIRPVAPMLI PHKANVDSSI GEFTVPKDTH VVVNLWALHH DENEWDQPDQ FMPERFLDPT GSHLITPTQS YLPFGAGPRS CIGEALARQE LFVFTALLLQ RFDLDVSDDK QLPRLEGDPK VVFLIDPFKV KITVRQAWMD AQAEVST
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Rat Steroid 17-alpha-hydroxylase / 17,20 lyase Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Rat Steroid 17-alpha-hydroxylase / 17,20 lyase Protein General Information | |
|---|---|
| Alternate Names | |
| Cyp17 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CYP17A1 |
| Entrez Gene ID | 25146 |
| RefSeq Protein Accession(s) | NP_036885.1 |
| RefSeq mRNA Accession(s) | NM_012753.2, XM_006231434.3, XM_006231435.3 |
| UniProt ID(s) | P11715 |
| UniGene ID(s) | Rn.10172 |
| COSMIC ID Link(s) | CYP17A1 |
| KEGG Gene ID(s) | rno:25146 |
| General Description of Recombinant Rat Steroid 17-alpha-hydroxylase / 17,20 lyase Protein. | |
| Conversion of pregnenolone and progesterone to their 17-alpha-hydroxylated products and subsequently to dehydroepiandrosterone (DHEA) and androstenedione. Catalyzes both the 17-alpha-hydroxylation and the 17,20-lyase reaction. Involved in sexual development during fetal life and at puberty. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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