PDF DatasheetHuman FcERI / FCER1A Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant FcERI / FCER1A based upon sequence from Human
Host: QP6026 protein expressed in E.coli, Yeast..
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) FcERI / FCER1A, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6026.
Bioactivity Data: Untested
Full Length? Extracellular Domain
Expression Region: Val26 – Gln205
Amino Acid Sequence: VPQKPKVSLN PPWNRIFKGE NVTLTCNGNN FFEVSSTKWF HNGSLSEETN SSLNIVNAKF EDSGEYKCQH QQVNESEPVY LEVFSDWLLL QASAEVVMEG QPLFLRCHGW RNWDVYKVIY YKDGEALKYW YENHNISITN ATVEDSGTYY CTGKVWQLDY ESEPLNITVI KAPREKYWLQ
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human FcERI / FCER1A Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human FcERI / FCER1A Protein General Information | |
|---|---|
| Alternate Names | |
| FcERI, FCER1A, fcepsilonri, Fce1a, FcERI, Fcr-5 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | FCER1A |
| Entrez Gene ID | 2205 |
| Ensemble Gene ID | ENSG00000179639 |
| RefSeq Protein Accession(s) | NP_001992.1 |
| RefSeq mRNA Accession(s) | NM_002001.3 |
| UniProt ID(s) | P12319 |
| UniGene ID(s) | Hs.897 |
| HGNC ID(s) | HGNC:3609 |
| COSMIC ID Link(s) | FCER1A |
| KEGG Gene ID(s) | hsa:2205 |
| PharmGKB ID(s) | PA28056 |
| General Description of Recombinant Human FcERI / FCER1A Protein. | |
| Binds to the Fc region of immunoglobulins epsilon. High affinity receptor. Responsible for initiating the allergic response. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators (such as histamine) responsible for the manifestations of allergy. The same receptor also induces the secretion of important lymphokines. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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