PDF DatasheetHuman Glutaminase kidney isoform, mitochondrial Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Glutaminase kidney isoform, mitochondrial based upon sequence from Human
Host: QP6095 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Glutaminase kidney isoform, mitochondrial, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6095.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Tyr370 – Leu669
Amino Acid Sequence: YVGFSNATFQ SERESGDRNF AIGYYLKEKK CFPEGTDMVG ILDFYFQLCS IEVTCESASV MAATLANGGF CPITGERVLS PEAVRNTLSL MHSCGMYDFS GQFAFHVGLP AKSGVAGGIL LVVPNVMGMM CWSPPLDKMG NSVKGIHFCH DLVSLCNFHN YDNLRHFAKK LDPRREGGDQ RVKSVINLLF AAYTGDVSAL RRFALSAMDM EQRDYDSRTA LHVAAAEGHV EVVKFLLEAC KVNPFPKDRW NNTPMDEALH FGHHDVFKIL QEYQVQYTPQ GDSDNGKENQ TVHKNLDGLL
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Glutaminase kidney isoform, mitochondrial Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Glutaminase kidney isoform, mitochondrial Protein (370-669aa) General Information | |
|---|---|
| Alternate Names | |
| GLS1, GAC, KGA, GAM, AAD20 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | GLS |
| Entrez Gene ID | 2744 |
| Ensemble Gene ID | ENSG00000115419 |
| RefSeq Protein Accession(s) | NP_001243239.1 |
| RefSeq mRNA Accession(s) | NM_001256310.1, NM_014905.4 |
| UniProt ID(s) | O94925 |
| UniGene ID(s) | Hs.116448 |
| HGNC ID(s) | HGNC:4331 |
| COSMIC ID Link(s) | GLS |
| KEGG Gene ID(s) | hsa:2744 |
| PharmGKB ID(s) | PA28734 |
| General Description of Recombinant Human Glutaminase kidney isoform, mitochondrial Protein (370-669aa). | |
| Catalyzes the first reaction in the primary pathway for the renal catabolism of glutamine. Plays a role in maintaining acid-base homeostasis. Regulates the levels of the neurotransmitter glutamate in the brain. Isoform 2 lacks catalytic activity. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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