PDF DatasheetHuman Glutaminase kidney isoform, mitochondrial Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Glutaminase kidney isoform, mitochondrial based upon sequence from Human
Host: QP6096 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Glutaminase kidney isoform, mitochondrial, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6096.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Lys616 – Leu669
Amino Acid Sequence: KDRWNNTPMD EALHFGHHDV FKILQEYQVQ YTPQGDSDNG KENQTVHKNL DGLL
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Glutaminase kidney isoform, mitochondrial Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Glutaminase kidney isoform, mitochondrial Protein (616-669aa) General Information | |
|---|---|
| Alternate Names | |
| GLS1, GAC, KGA, GAM, AAD20 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | GLS |
| Entrez Gene ID | 2744 |
| Ensemble Gene ID | ENSG00000115419 |
| RefSeq Protein Accession(s) | NP_001243239.1 |
| RefSeq mRNA Accession(s) | NM_001256310.1, NM_014905.4 |
| UniProt ID(s) | O94925 |
| UniGene ID(s) | Hs.116448 |
| HGNC ID(s) | HGNC:4331 |
| COSMIC ID Link(s) | GLS |
| KEGG Gene ID(s) | hsa:2744 |
| PharmGKB ID(s) | PA28734 |
| General Description of Recombinant Human Glutaminase kidney isoform, mitochondrial Protein (616-669aa). | |
| Catalyzes the first reaction in the primary pathway for the renal catabolism of glutamine. Plays a role in maintaining acid-base homeostasis. Regulates the levels of the neurotransmitter glutamate in the brain. Isoform 2 lacks catalytic activity. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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