PDF DatasheetHuman Heme oxygenase 1 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Heme oxygenase 1 based upon sequence from Human
Host: QP6172 protein expressed in E. coli.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Heme oxygenase 1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6172.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Arg3 – Met288
Amino Acid Sequence: RPQPDSMPQD LSEALKEATK EVHTQAENAE FMRNFQKGQV TRDGFKLVMA SLYHIYVALE EEIERNKESP VFAPVYFPEE LHRKAALEQD LAFWYGPRWQ EVIPYTPAMQ RYVKRLHEVG RTEPELLVAH AYTRYLGDLS GGQVLKKIAQ KALDLPSSGE GLAFFTFPNI ASATKFKQLY RSRMNSLEMT PAVRQRVIEE AKTAFLLNIQ LFEELQELLT HDTKDQSPSR APGLRQRASN KVQDSAPVET PRGKPPLNTR SQAPLLRWVL TLSFLVATVA VGLYAM
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Heme oxygenase 1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Heme oxygenase 1 Protein General Information | |
|---|---|
| Alternate Names | |
| HO-1, HMOX1D, HSP32, bK286B10 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | HMOX1 |
| Entrez Gene ID | 3162 |
| Ensemble Gene ID | ENSG00000100292 |
| RefSeq Protein Accession(s) | NP_002124.1 |
| RefSeq mRNA Accession(s) | NM_002133.2 |
| UniProt ID(s) | P09601 |
| UniGene ID(s) | Hs.517581 |
| HGNC ID(s) | HGNC:5013 |
| COSMIC ID Link(s) | HMOX1 |
| KEGG Gene ID(s) | hsa:3162 |
| PharmGKB ID(s) | PA29341 |
| General Description of Recombinant Human Heme oxygenase 1 Protein. | |
| He oxygenase cleaves the he ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of he oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Exhibits cytoprotective effects since excess of free he sensitizes cells to undergo apoptosis. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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